It's Spreading?!
This type of skin cancer has the lowest metastatic potential.
What is basal cell carcinoma?
Merkel cell carcinoma most commonly show up on the body in these places.
What is the head and neck?
This type of skin cancer is spotted with its characteristic "keratin pearls".
What is squamous cell carcinoma (SCC)?
Name a topical agent that is helpful in prevention of skin cancer.
What is sunscreen?
This form of melanoma is more commonly seen in African-Americans and Asians.
What is acral lentiginous melanoma?
How do (most) carcinomas spread through the body?
Lymph vessels
This type of skin cancer is more commonly associated with a secondary scale on the lesion.
What is squamous cell carcinoma?
Name one subtype of Merkel cell carcinoma based on histopathology.
This type of surgery is commonly used to microscopically remove cancerous lesions.
What is Mohs surgery?
This is the virus behind most Merkel cell carcinomas.
What is the Merkel cell polyomavirus (MCPyV)?
The test used to stage Merkel cell carcinoma without visible lymphadenopathy.
What is sentinel lymph node biopsy?
This is a tumor that looks like SCC but regresses on its own after rapid growth.
What is keratoacanthoma?
Basal cell carcinoma often presents with this fence-like structure on the outer rim of its nodules.
What are palisading nuclei?
This drug, in BRAF-mutated melanoma, may be useful in improving prognosis.
What is vemurafenib?
What type of ultraviolet radiation is linked to increased risk of skin cancer?
Both UVA and UVB
This measure correlates with risk of metastasis.
Name each portion of the ABCDE criteria for melanoma diagnosis (must be specific with D).
What is asymmetry, irregular borders, color variation, diameter > 6mm, and evolving over time?
This commonly associated and specific marker can help identify Merkel cell carcinoma from other tumors of the skin.
What is cytokeratin 20 (CK20)?
This nucleotide analog may be used to treat basal cell carcinoma via a topical cream.
What is 5-fluorouracil?
This nutrient deficiency increases risk for squamous cell carcinoma.
What is vitamin A deficiency?
Name the two locations that melanoma commonly metastasizes to.
What are the lungs and the brain?
A blue-black hue on dermoscopy raises suspicion for this subtype of melanoma.
What is nodular melanoma?
This lung cancer looks similar to Merkel cell carcinoma on histology.
What is small-cell lung cancer?
This class of immunotherapy is approved in the management of complicated/metastatic Merkel cell carcinoma.
What are anti-PD1 monoclonal antibodies?
This cell is behind Merkel cell carcinoma.
It is actually unclear, and it is hypothesized that MCPyV positive and negative tumors actually may have two separate origins of multipotent stem cells.