Prevention
Infection
Epidemiology
History
Eradication
100
Who came up with the idea of vaccinating people with cow pox to prevent a smallpox infection? In what year? (extra 100 pts)
Who is Edward Jenner in 1796
100
How long is the incubation period?
What is 10 to 14 days (usually 12 days)
100
In an unvaccinated population, the CFR for variola major is?
20% estimated in from the Indian subcontinent, higher in the Americas (newly susceptible populations)
100
In the devastating 1874 outbreak in this US city, only 174 susceptible persons escaped infection.
What is Boston
100
What is the difference between elimination and eradication?
elimination - regional eradication - global
200
In honor of Jenner, who generalized the use of the term "vaccination" to include preventative inoculation with all kinds of infectious agents?
Who is Pasteur (in 1881)
200
Name of the virus variants of Smallpox?
What are variola major and Variola minor
200
What is/are the reservoirs for small pox virus?
humans are only reservoir
200
What proportion of the Aztec population died within 6 months of the introduction of smallpox?
What is 50%
200
The last case of Variola minor occured in what country and what year?
What is Somalia in 1977
300
What is variolation?
Innoculation using smallpox scabs
300
How long does immunity last after infection?
What is lifelong
300
The CFR for variola minor is?
What is 1%
300
This Egyptian Pharaoh likely died from smallpox
Who is Ramses V
300
What medical instrument is credited with greatly assisting in eradication?
What is the bifurcated needle
400
Where and when are the origins of variolation?
10th century - in China and India
400
What family does the smallpox virus belong to?
What is Poxviradae
400
Smallpox showed a spike in incidence in which season/s?
What is winter/spring
400
The first importation of smallpox to the new world occurred here in 1507
What is Hispaniola
400
Name the two labs where live smallpox virus is kept.
CDC, Atlanta Vektor Lab, Novosibirsk, Russia
500
Who is credited with introducing variolation to Great Britain in 1721?
Who is Lady Mary Wortley Montagu
500
Name two infections/syndromes whose symptoms mimic those of smallpox?
monkeypox, chickenpox
500
What is Ro?
What is 5-7
500
This Yoruba diety is the god of smallpox
What is Sapono (aka Obaluaye or Omolu)
500
In what year was the WHO intensified smallpox eradication program established?
What is 1966
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