Types
What is the most common metastatic site for a myxoid liposarcoma?
Lungs
Which imaging modality is most useful to diagnose soft tissue masses?
MRI
Limb-sparing resection
What does STS stand for?
Soft tissue sarcoma
These types of sarcomas are highly associated with NF-1
Malignant peripheral nerve sheath tumors
What imaging characteristic on MRI is highly suspicious for a sarcoma?
Heterogeneously enhancing soft tissue mass deep to the fascia
T or F: Recent studies showed preoperative radiation has no improvement in recurrence-free survival for retroperitoneal sarcomas
TRUE
What is the CARE diagnoses?
Clear cell sarcoma, angiosarcoma, rhabdomyosarcoma, Ewing sarcoma
Most sarcomas are usually found deep to fascia except there two
Dermatofibrosarcoma protrubens and Myxofibrosarcoma
T or F: SLNB should always be done for staging purposes for all types of sarcomas
FALSE
What is the size (in cm) and histologic grade cutoff to consider chemotherapy in sarcomas?
Large (>5 cm per AJCC), high grade
What is the most recognized etiologic factor for STS?
Radiation exposure
What is the difference between atypical lipomatous tumors and well differentiated liposarcoms?
Location. ALT in extremities and WDLS are in retroperitonium.
What are the three tiers of FNCLCC histologic grading system for sarcomas?
Low, intermediate, high
What is considered an R0 resection per AJCC?
No tumor on excision margin (recent consideration for R0 + 1mm but not official, bone periosteum for tumors abutting a long bone)
How many cases of STS are diagnosed every year?
13,000
What is the most common sarcoma in the hand?
Epithileoid sarcoma
What are three components of the AJCC's prognostic staging system for STS?
Tumor histologic grade, size and nodal/visceral metastatic disease (Depth is no longer one of them)
What is the range of radiation dose used for sarcomas? (in Gy)
50-66
Angiosarcomas are closely associated with chronic lymphedema. This is also known as?