Stem Cell Properties
Types of Stem Cells
Applications to Eye
Scientists and Careers
100

Name three types of cells that a stem cell can become

Literally any cell in the body can work!

100

What does iPSC stand for?

Induced pluripotent stem cells

100

List two potential causes of blindness

Potential answers include:

Diabetes, macular degeneration, corneal/retinal infections, glaucoma, cataracts, lens clouding, change in eye shape, retinal deterioration, optic nerve damage

100

At which institution is Dr. Sangeeta Bhatia a professor (as of Dec 2019)?

MIT

200

What are the three main types of potency?

Pluripotency, totipotency, multipotency

200

Which type of stem cell has the least potency?

Adult stem cells

200

What are the two types of photoreceptors in the eye?

Rods and cones

200

Dr. Mahendra Rao is the director for which center of the NIH?

Regenerative Medicine

300
What causes stem cells to differentiate?

Internal and external factors/signals

300

What are the three different germ layers?

Endoderm, ectoderm, and mesoderm

300

Which type of photoreceptor is responsible for your perception of color?

Cones
300

What is the name of the woman scientist who left her career in law for a career researching diabetes?

Susan Solomon

400

What is a progenitor cell?

A cell that is more differentiated than a stem cell, which divides and pushes differentiation towards a target cell.

400

Where are embryonic stem cells derived from?

Inner cell mass of the blastocyst

400

What part of the eye is most commonly treated for disease using stem cell therapies?

Cornea
400

For what was Dr. Shinya Yamanaka awarded a Nobel Prize?

The discovery of the four "Yamanaka" factors and their ability to induce pluripotency in adult fibroblast cells 

500

How do stem cells achieve "immortality"?

Asymmetrical and symmetrical division to produce identical stem cells

500

What are the four factors used to induce pluripotency in iPS cells?

Oct3/4, Klf4, Myc, and Sox2

500

What different parts of the cornea have researchers tried to engineer?

Corneal stroma, epithelium, endothelium, innervation
500

Who is the most cited engineer in history?

Dr. Robert Langer

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