SuperCalifFragilisticStemCells
Sources and Alternatives
Hammers and Pliers and Saws, Oh My (the CBR Toolkit)
A Stem Cell a Day Keeps the Doctor Away
Matchmaker, Matchmaker, Make Me a Match
100
These cells give rise to the blood and immune system.
What are hematopoietic stem cells?
100
This connects baby to mom during pregnancy
What is the umbilical cord?
100
This is the type of anticoagulant is used in CBR's cord blood collection kit
What is lyophilized heparin?
100
A type of cancer of the blood
What is leukemia? What is lymphoma?
100
This is the role of the HLA markers and is used to determine compatibility, based on an adequate match for stem cell transplants in an allogeneic transplant
What is distinguishing cells that are "self" vs. "non-self" based on inherited genetic markers?
200
These stem cells resources, which can be collected shortly after a baby is born, are stored by CBR
What is umbilical cord blood and/or tissue?
200
Used for over 40 years as a treatment option for patients with leukemia
What is bone marrow or bone marrow transplant?
200
This component of CBR's collection kit was designed to help the collector maximize the volume of cord blood collected
What is the ActiveFlo Chamber?
200
DAILY DOUBLE! Cord blood is being investigated as a potential treatment for conditions such as cerebral palsy in this field of medicine
What is regenerative medicine?
200
The odds that two full siblings are an exact HLA match to one another.
What is 1 in 4? What is 25%
300
These cells give rise to structural and connective tissues.
What are mesenchymal stem cells?
300
Many of us have too much of this source of mesenchymal stem cells
What is adipose tissue?
300
This feature of CBR's collection kit provides a sterile method for clearing residual blood from the tubing after the collection
What is the Sterile Clearance Vent?
300
Stem cells are a treatment option for certain blood and immune cancers (such as leukemia) in this field of medicine
What is transplant medicine?
300
DAILY DOUBLE! HLA stands for this
Human Leukocyte Antigen
400
CBR is primarily focused on these two types of newborn stem cells, although other cell types found in newborn tissues may also have potential future applications
What are MSCs and HSCs?
400
DAILY DOUBLE! This is the median amount of blood collected in family banks
What is 60cc?
400
DAILY DOUBLE! This device allows for detection in case the needle is lost
What is the Radiopaque needle cover?
400
This type of stem cell transplant uses the patient's own stem cells.
What is autologous?
400
After chemotherapy and radiation destroys the disease-causing cells, this is how the stem cells are administered in a stem cell transplant
What is through a simple intravenous (IV) infusion?
500
DAILY DOUBLE! These are two properties of newborn HSC's from cord blood
What is they have low risk of viral contamination? What is they have the ability to differentiate into various cell types? What is they have a high proliferation capacity? What is they have a low risk of tumor formation? What is they have capacity for autologous transplantation? What is they have established/proven treatment in human patients?
500
An alternative to bone marrow harvesting, this method uses drugs to mobilize hematopoietic stem cells from the bone marrow into the blood
What is peripheral stem cell collection?
500
These are several reasons why CBR’s anticoagulant, lyophilized heparin (LH), is advantageous over the commonly used liquid citrate phosphate dextrose (CPD)
What is helps provide the collector with a more accurate view of collection volume during the cord blood collection? What is helps maintain cell viability and concentration during transit?
500
This type of transplant uses stem cells from someone else donated to the patient receiving the stem cell transplant
What is allogeneic?
500
HLA markers are used/recognized by this body system
What is the immune system?
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