Advanced Clinical Care
Diagnostics/Imaging
Biostats
CCS Cases
Multisystem
100

A 62-year-old with atrial fibrillation presents with acute onset right arm weakness and aphasia <4.5 hrs after onset. Next step?

Answer: What is administer IV alteplase?

100

Best initial test for suspected DVT in a stable patient?

Answer: What is compression ultrasonography?.

100

Type I error measures what probability?

Answer: What is false positive rate (α)?

100

CCS: Patient with DKA arrives; initial order for metabolic stabilization?

Answer: What is IV fluids + insulin drip?

100

Antibiotic of choice for hospital-acquired pneumonia with risk for Pseudomonas?

Answer: What is piperacillin–tazobactam (or meropenem)?

200

A patient with STEMI has persistent chest pain despite aspirin and nitroglycerin. ECG shows inferior ST elevation. Next best intervention?
Answer: What is emergent percutaneous coronary intervention?

Answer: What is emergent percutaneous coronary intervention?

200

In suspected subarachnoid hemorrhage with negative CT within 6 hrs, next best test?

Answer: What is lumbar puncture for xanthochromia?

200

A patient refuses life-saving blood transfusion due to religious beliefs; capacity intact. Ethical principle guiding respect?

Answer: What is autonomy?

200

CCS: CHF patient with acute pulmonary edema; next priority after oxygen?

Answer: What is IV diuretics (furosemide)?

200

Initial management for suspected pulmonary embolism with hypotension?

Answer: What is emergent thrombolysis?

300

A 50-year-old with new-onset diabetes and weight loss has a palpable non-tender gallbladder. Most likely diagnosis?

Answer: What is pancreatic adenocarcinoma (Courvoisier sign)?

300

A patient with acute abdomen and free air under diaphragm on upright film. Most likely cause?

Answer: What is perforated viscus?

300

You perform a study with p = 0.03. Interpret this?

Answer: What is there is a 3% probability that the observed effect is due to chance if the null is true?

300

CCS: Severe asthma exacerbation tiring and hypoxic despite albuterol; next escalate?

Answer: What is IV magnesium and consider non-invasive ventilation?

300

An elderly with suspected temporal arteritis and vision changes; next best step before biopsy?

Answer: What is high-dose steroids?

400

A patient with suspected bacterial meningitis cannot receive LP before antibiotics due to signs of increased intracranial pressure. Immediate next step?

Answer: What is start empiric broad-spectrum antibiotics and steroids?.

400

A melanoma-suspected skin lesion biopsy technique?

Answer: What is excisional biopsy with narrow margins?

400

Confidential patient info is mistakenly posted online. What is required?

Answer: What is HIPAA breach notification and mitigation?

400

CCS: Suspected sepsis with HR 120, hypotension after fluids; first vasopressor?

Answer: What is norepinephrine infusion?

400

A patient with hypercalcemia and EKG changes (short QT, arrhythmia); immediate treatment?

Answer: What is IV fluids + calcitonin?

500

A 27-year-old with shortness of breath and elevated D-dimer has borderline creatinine limiting CT contrast. Next diagnostic step?

Answer: What is ventilation–perfusion (V/Q) scan?

500

febrile neutropenic patient with persistent fever despite IV antibiotics; next imaging?

Answer: What is chest CT for invasive fungal disease?

500

You design a trial comparing 3 therapies and want to control for multiple comparisons. Appropriate method?

Answer: What is Bonferroni correction?

500

CCS: Upper GI bleed with hemodynamic instability; first action before blood products?

Answer: What is airway protection + fluid resuscitation + type and cross?

500

Young patient with acute ischemic stroke arrives just outside thrombolytic window but with small core infarct and large penumbra on MRI; next action?

Answer: What is mechanical thrombectomy if within time criteria?

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