Penumbra Sucks
New AHA Guidelines
Solitaire Stands Alone
New Era of Evidence
Cant Stop Wont Stop
100
What was the observed rate of SICH in Penumbra's Therapy Trial?
What is 11%
100
This is the recommended NIH Stroke Scale to identify and treat an LVO?
What is NIH > 6
100
These are the two primary takeaways from the Landmark Solitaire Data presented at ISC 2015.
What is, twice the rate of good neurologic outcomes and 1/2 reduction in mortality vs. TPA alone.
100
This is the rate of good neurologic outcomes in Swift Prime
What is 60% intervention vs. 35% TPA
100
This is what Dr. Elad Levy (Buffalo) says about Solitaire in comparison to Trevo
What is it is more "supple?" (Bending and moving easily and gracefully, flexible.)(Limber, agile, graceful.)
200
In Penumbra's 2007 Pivotal trial, recanalization rates were observed at 82%. Despite this high rate of recanalization, what was the rate of Good Clinical Outcomes?
What is 25%
200
This is the recommended treatment window for LVO occlusions
What is < 6 hours LKW - 8 HR On label, 12 with advanced imaging.
200
This is the rate of SICH in Swift Prime and Extend-IA?
What is 0%
200
This is the rate of Good Neurologic outcomes in Extend-IA
What is 71% intervention vs 40% TPA
200
This is the consistently observed SICH rate for Trevo
What is 7%
300
In ADAPT FAST, Penumbra states that we have moved beyond being satisfied with recanalization. Instead, we need to focus on quality of thrombectomy & likelihood of good outcomes. Has Penumbra proven that their direct aspiration treatment of LVO's provides patients with better good neurologic outcomes vs. TPA alone?
What is NO - 38% Good MRS in Therapy vs. 30% Good MRS TPA.
300
This is the recommended imaging tool for identifying an LVO
What is CTA
300
These trials, in consecutive order, have the following rates of Good Neurologic Outcomes - 71% vs. 40%, 60% vs. 35% and 53% vs. 29%?
What is Extend-IA (Australia) Swift Prime (U.S) and Escape (Canada)
300
This is the rate of good neurologic outcomes in Escape
What is 53% Intervention arm vs. 29% TPA
300
This is the consistent rate of total emboli in Solitaire studies
What is < 2%
400
This is the rate of Large Downstream Emboli in the ADAPT Fast Study?
What is 16% - Solitaire less than 2% Total Emboli in STAR.
400
This is the recommended treatment for patients with an identified LVO
What is Stent Thrombectomy (Level 1A evidence.)
400
This is the amount of money Medtronic invested in Clinical Trials to advance the standard of stroke care
What is 25 million
400
This is the rate of Good Neurologic Outcomes in MR Clean
What is 33% in Intervention arm vs. 19% in TPA arm
400
What is the secret sauce to the Solitaire device?
What is "Parametric Design" - Overlap
500
This percentage of patients are "lost to follow up" in Penumbra's ADAPT Fast reported data?
What is 23% - Included to reduce mortality, excluded to increase good clinical outcomes.
500
This is the number of patients treated last year in the US with Mechanical Thrombectomy
What is 20,000 (up from 13,000 previous year)
500
This is the rate of TICI 2B/3 Recanalization in SWIFT Prime?
What is 88%
500
This is the number of landmark stroke trials that involved the Solitaire device
What is 5
500
These are the countries that presented landmark stroke trial data
What is the Netherlands, U.S., Australia, Canada and Spain.
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