Basics
What 3 components make DNA?
Deoxyribose sugar, phosphate group, nitrogenous base. A T C G
What bonds hold the nitrogenous bases between the base pairs of the two strands of DNA together?
H - Bonds
Nucleosomes
DNA is attracted to a protein called histones. DNA wraps around a histone cluster In the nucleus making a structure called nucleosomes
What radio isomer picks up DNA?
P32
Who experimented with mice and pneumonia?
Griffith
Describe the difference between purines and pyrimidines and name their nitrogenous bases.
Purines are 2 rings (1 5 sides 1 6 sides) ( A & G )
Pyrimidines is a 1 6-sided ring ( T & C )
Purines + Pyrimidines is the pairing
What direction does DNA strands run in relation to each other?
antiparallel
Supercoils
Chromatin coils onto its self again creating the basic structure that make up chromosomes
What radio isomer picks up protein?
S^35
What carries the information to create new phage?
DNA
What are the monomers of DNA called?
Nucleotides
Who was credited for discovering the structure?
Watson and crick
Part of DNA similar to the sides of a ladder?
Sugar phosphate background
What did Hershey and Chase discover in their experiment conclusion?
DNA was the hereditary genetic material of the virus
What are the three types of replication?
Conservative, semi-conservative, dispersive
What bond is between a deoxyribose sugar and nitrogen base?
glycosidic bond
What two things make up the backbone of DNA?
Phosphate and sugar
What is the main structure of DNA itself?
Double helix
Who is responsible for determining the percentages of the base pairs?
Chargoff
What nonradioactive isotopes creates the heavy and light DNA?
Heavy: N15
Light: N14
What bond is between a deoxyribose sugar and a Phosphate group?
ester or phosphodiester bond
Whats the sugar in the structure of RNA?
Ribose
What is the larger part of the nitrogenous base with 2 rings?
Purines
What part of the DNA structure can change?
Nitrogenous bases
What was Meselson and stalls conclusion?
DNA replication is semi conservative