Effects
Use
In the Brain
Treatment
Random
100

Includes feelings of relaxation, drowsiness, or confusion, nausea, vomiting, constipation, slowed breathing.

Effects of short term opioid use 

100

Taking the medicine in a way or dose other than prescribed, taking someone else's prescription medicine, or taking the medicine to get high.

Opioid Misuse/Abuse

100

These are the receptors in the brain, spinal cord, and other organs to which opioids bind. 

Opioid receptors 

100

Life-saving medication that can reverse the effects of an opioid overdose. 

Naloxone (Narcan) 

100

Butterflies use this body part to taste.

Feet

200

Includes addiction, insomnia, heart problems, and pneumonia.

Effects of long term opioid use 

200

When opioids are taken for a short time, as prescribed by a doctor for pain relief or other medical issues.

Safe Opioid Use 

200

Opioid receptors regulate these functions in the body.

Respiratory and GI function, mood, pain, reward, and stress.

200

A type of behavioral therapy used in treating opioid use disorder that focuses on changing negative thought patterns and behaviors into healthier ones.

Cognitive Behavioral Therapy (CBT)

200

This planet in our solar system has the hottest surface temperature.

Venus

300

Confusion, respiratory arrest, extreme sleepiness, pinpoint pupils, and intermittent loss of consciousness. 

Signs of an overdose.
300

Appears as a white or brown powder or a black sticky substance, can be injected, snorted, or smoked. 

Heroin

300

This happens when the brain's opioid receptors become less sensitive to the drug, requiring higher concentrations of the opioid to achieve the same level of effect.

Tolerence
300

A treatment method involving the use of medications like Suboxone and Methadone, along with behavioral therapy to treat substance use disorder.

Medication Assisted Treatment (MAT)

300

This number is represented by "V" in Roman numerals. 

5

400

Anxiety, nausea, vomiting, or abdominal pain occurring after suddenly stopping use.

Withdrawal symptoms

400

Examples include illicit fentanyl and heroin. 

Illegal opioids
400

A substance that "mimics" the effects of another, binding to the same receptors in the brain to help reduce cravings.

Agonist

400

These are opioid agonists that are used in Medication Assisted Treatment (MAT).

Methadone and buprenorphine

400

The process plants use to convert sunlight into food.

Photosynthesis

500

An effect of heroin use, where the brain does not receive enough oxygen - which can lead to permanent brain damage and death.

Hypoxia

500

Examples include: Hydrocodone, oxycodone, morphine, codeine, and fentanyl.

Prescription pain relievers (legal opioids)

500

A substance that blocks a receptor, preventing another from binding to it. 

Antagonist

500

This is an opioid antagonist used in Medication Assisted Treatment (MAT).

Naltrexone

500

This musical artist was the headline performer for the 2024 Super Bowl. 

Usher

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