SSI Risk Factors
Anesthesia SSI Prevention Bundle
All Things Antibiotics
SSI Miscellaneous
100

This modifiable risk factor not only affects lung health, but also decreases your immune response to pathogens.

What is smoking?

100

This class of medication is prophylactically given before surgical incision.

What are antibiotics?

100

The most frequent antibiotic given for surgical SSI prophylaxis.

What is cefazolin/Ancef?

100

110mg/dL - 200mg/dL is the ideal range for this lab value.

What is blood glucose?

200

Ozempic, now used broadly for weight loss, was intended to control this disease process.

What is diabetes?

200

In the operating room, we use a Bair Hugger to maintain this function.

What is normothermia?

200

Unlike cefazolin which should be administered within 60min of surgical incision, vancomycin should be administered within this time frame before incision.

What is 120min?

200

Intraoperative normothermia range in Celsius.

What is 35.5 to 36 degrees Celsius?

300

A 2014 survey conducted by Harris Poll on behalf of Pfizer showed that 87% of Americans have a fear of this.

What is aging?

300

Because surgical stress increases cortisol, it is important to maintain this lab value in order to maintain neutrophil/immune function.

What is blood glucose?

300

These two factors dictate redosing of antibiotics.

What is the passing of 2 half-lives of the antibiotic of choice or 1500mL blood loss?

300

It is recommended to check intraoperative blood glucose in patients who have received insulin therapy with this frequency.

What is every 2 hours?

400

This condition, predominantly found in impoverished areas, delays wound healing.

What is malnutrition?
400

Though blood transfusions can increase the risk for SSIs, it is important to maintain this function to prevent hypoperfusion or tissue edema/local inflammation.

What is normovolemia?

400

Cross-sensitivity between penicillin allergy and cephalosporins is due to similarities between this specific chemical structure.

What is an R1 side chain?

400

This form of insulin administration provides prolonged glucose control.

What is subcutaneous injection OR IV insulin infusion?

500

Along with surgical sterility and staff hygiene, the failure to appropriately administer this class of medication can increase the risk of infections.

What are antibiotics?

500

A 2009 meta-analysis showed that providing higher amounts of this substance (80% vs 30%) during general anesthesia lowered the risk of SSI.

What is supplemental O2?

500

These two antibiotics are reasonable surgical prophylactic alternatives for patients who are allergic to beta lactam antibiotics.

What are vancomycin and clindamycin?

500

Even though providing intraoperative supplemental O2 can decrease risk of SSI, caution must be taken toward providing prolonged high levels of O2 due to the risk of this.

What are free radicals --> oxidative stress --> tissue damage?

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