Diagnosis
TB Disease
MDR TB
Contact Investigations
Potluck
Final Jeopardy
100
What are the symptoms of TB disease?
Cough of 3 weeks, bloody sputum, and chest pain
100
Who has the primary responsibility for ensuring successful completion of TB treatment.
What is the TB program? (including the TB clinician, nurse case manager and DOT/DIS outreach staff.)
100
This is defined as M. tb that is resistant to at least INH and RIF.
What is MDR TB?
100
True or False: The index patient represents the first instance or initial report of TB disease.
What is true?
100
These tiny air sacs in the lungs are where TB bacilli can multiply and cause infection.
What are alveoli?
200
This blood test measures a person's immune response to M.tb
What is an IGRA
(Interferon-Gamma Release Assay)?
QuantiFERON®-TB Gold Plus;
T-SPOT®.TB test (T-Spot)
200
This term refers to the ability of a drug to rapidly kill multiplying M. tb.
What is bactericidal?
200
Previous TB and poor adherence to TB treatment are ____ for drug resistant TB.
What are risk factors?
200
This establishes a probable start and end point of potential transmission between the index patient and contacts.
What is the infectious period?
200
These are the three most preferred short course options for treating TB infection.
What are
3HP (12 weeks of INH + Rifapentine)
and
4R (4 months of Rifampin)
and
3 HR?
300
This is what laboratory personnel look for in a smear.
What are acid-fast bacilli (AFB)?
300
This the 6-month regimen for treating drug susceptible TB in adults.
1) An intensive phase of _____months of ______________________followed by
2) a continuation phase of _____months of ________________________.
What are an intensive phase of 2 months of RIPE followed by a continuation phase of 4 months of INH and RIF?
300
This type of resistance develops during TB therapy.
What is secondary (or acquired) resistance?
300
This is an environment where a number of people gather or share the same air space for either a limited or extended period of time.
What is a congregate setting?
300
This is the gene that confers resistance for Rifampin.
What is rpoB?
400
This type of pattern on the chest X-ray results from hematogenous dissemination of the tubercle bacilli leading to many nodules of varying sizes in the interstitium and airspaces. 
What is miliary TB?
400
This new shorter regimen was shown in a landmark study to be as effective as the current 6-month regimen for treatment of TB.
(Hint: months and drugs)
What is 2HPMZ and 2HPM?
400
QTC prolongation is a side effect of______.
What is bedaquiline and moxifloxacin?
400
This model can help set parameters, define the limits, and help visualize the information collected in a contact investigation.
What is concentric circle model of contact tracing?
400
He discovered the bacteria that causes TB.
Who is Robert Koch?
500
A patient has cough, fever, and hemoptysis with an abnormal CXR. Symptoms and imaging improve with RIPE, however, AFB smears and culture are negative. What type of TB is this?
What is "clinical" or culture negative TB?
500
Completion of treatment is primarily defined by this within a specific time frame.
What is the number of ingested doses?
500
This short-course option for treatment of MDR TB uses an oral regimen for 6 months.
What are the BPaL or BPaLM regimens?
500
True or False:
The minimum infectious period should be 3 months before symptom onset in the setting of a case with smear positive cavitary TB.
What is True?
500
True or False:
A 4-month regimen for TB disease including rifapentine, isoniazid, ethambutol and pyrazinamide was non-inferior to the standard 6- month regimen.
What is False?
500
Name this Nicole Kidman movie in which the main character that she plays dies of TB.
What is Moulin Rouge?