What is the brand name for Amitriptyline?
What is the drug class of Imipramine?
Tricyclic Antidepressant
What dosage forms does Amitriptyline come in?
Tablet, solution
Name a common side effect of TCAs.
Dry mouth
Should TCAs be taken with or without food?
With food to reduce GI upset
True or False: Doxepin is also call Sinequan
True
Amitriptyline is primarily used to treat what mental health disorder?
Depression
Nortriptyline typically starts at what daily dose?
5–75 mg/day
What is a potentially fatal adverse effect of Amitriptyline overdose?
Cardiac arrhythmia
What vital sign should be monitored closely?
Heart rate – risk of tachycardia/arrhythmias
Which TCA’s brand name is Tofranil?
Imipramine
Name 2 off-label uses of Nortriptyline.
Chronic pain, migraine prophylaxis
Doxepin capsules come in what dosage strengths?
10 mg, 25 mg, 50 mg, 75 mg, 100 mg, 150 mg
Which side effect may require discontinuation of Nortriptyline?
Seizures
When should TCAs be administered – morning or night?
At night due to sedation
Pamelor is also know as?
Nortriptyline
Doxepin is used to treat anxiety and what type of insomnia?
Maintenance insomnia
Which TCA is available in a topical cream for itching?
Doxepin
What is the anticholinergic side effect triad?
Dry mouth, constipation, urinary retention
Before starting TCAs, what should the nurse assess?
Suicidal ideation, cardiac history, baseline EKG
Name all 4 TCAs with their brand equivalents.
Amitriptyline – Elavil
Imipramine – Tofranil
Doxepin – Sinequan
Nortriptyline – Pamelor
Which TCA can be used to treat childhood enuresis?
Imipramine
Which TCA is available in both oral and topical forms, and what condition can the topical form treat?
Doxepin
Why must TCAs be used cautiously in the elderly?
Risk of sedation, falls, confusion
What signs of toxicity should a nurse watch for?
Confusion, agitation, seizures, cardiac issues