Dosing
Administration
Contraindications
Why TNK?
Quality Metrics
100

What is the maximum dose for Tenecteplase

What is 25mg

100

How many IVs are required?

What is 1

100

What is the lowest acceptable blood sugar?

What is 50

100

Which has a shorter prep time, tPA or TNK?

What is TNK

100

What is door to decision time goal?

What is less than 20 minutes

200

What is the dosing on the box designed for use in

What are STEMIs

200

How must you combine the dilutent and the powdered medication?

What is swirl the mixture

200

How many months out must the patient be from a previous stroke to obtain Tenecteplase?

What is 3 months

200

How would the RN monitor the vitals of a patient receiving TNK?

What is the same as tPA - q15min for 2 hours then q30min for 6 hours
200

What is door to needle goal time?

What is less than 30 minutes

300

What is the proper weight based dosage for all patients?

What is 0.25mg/kg

300

What substance must be flushed out of a line prior to infusing Tenecteplase?

What is Dextrose

300

What is the maximum blood pressure acceptable for Tenecteplase administration?

What is a bp less than 185/110

300

How is angioedema monitored in the TNK patient?

What is q15min for 2 hours then q30min for 6 hours
300

How many neurons are lost with every minute of delayed revascularization?

What is 1.9 million neurons

400

How much dilutent is added to the mixture?

What is 10mL

400

How fast can Tenecteplase be pushed?

What is over 5 seconds

400

What is the timeframe that would disqualify a patient with a GI Bleed

What is a GI bleed within the past 21 days 

400

What is the time frame difference in tPA vs TNK administration?

What is 5 second push with TNK vs a bolus and 1 hour drip with tPA

400

What is door to ERT goal time for internal candidates?

What is less than 90 minutes

500

How much medication should be initially withdrawn from the syringe?

What is the maximum dose (25mg)

500

How do you obtain the drug?

What is call ED pharmacist who will have it with them in the red backpack at all Code Strokes

500

What is the proper coagulaopathy in order to receive Tenecteplase?

What is platelets greater than 100,000/mm3, INR < 1.7, aPTT < 40 and PT < 15
500

How do you order Tenecteplase?

What is Order Set: IV Thrombolytics

500

What is goal time for door to ERT for outside transfers?

What is less than 60 minutes

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