Thyroid Disorders
Adrenal Disorders
Pituitary + DI/SIADH
Endocrine Surgeries
Endocrine Medications
100

A patient presents with heat intolerance, weight loss, and tachycardia. What disorder is most likely? 

A. Hypothyroidism

B. Hyperthyroidism

C. Addison's disease

D. SIADH 

Answer: (B) Hyperthyroidism 

Rationale: Hyperthyroidism speeds up metabolism, so the patient often has heat intolerance, weight loss, tremors, anxiety, and tachycardia. 

100

Which condition is associated with excess cortisol?

A. Addison's disease

B. Cushing syndrome

C. Hypothyroidism

D. SIADH

Answer: (B) Cushing syndrome

Rationale: Cushing syndrome occurs when cortisol is too high. Cortisol excess causes hyperglycemia, hypertension, central weight gain, think skin, and infection risk. 

100

Which condition causes excessive dilute urine?

A. SIADH

B. Diabetes insipidus 

C. Hyperthyroidism 

D. Cushing syndrome

Answer: (B) Diabetes insipidus

Rationale: DI is caused by too little ADH or poor kidney response to ADH. Without ADH effect, the kidneys cannot retain water, causing large amounts of dilute urine.

100

Which surgery removes part of all the thyroid gland?

A. Hypophysectomy

B. Thyroidectomy

C. Adrenalectomy

D. Cholecystectomy 

Answer: (B) Thyroidectomy

Rationale: A thyroidectomy is removal of part of all of the thyroid gland, often done for thyroid cancer, severe hyperthyroidism, goiter, and nodules.

100

Which medication treats hypothyroidism?

A. Levothyroxine

B. Methimazole

C. PTU

D. Regular insulin

Answer: (A) Levothyroxine

Rationale: Levothyroxine is a synthetic thyroid hormone used to replace how thyroid hormone in hypothyroidism. 

200

Which lab pattern indicates primary hypothyroidism?

A. Low TSH, high T4

B. High TSH, low T4

C. High sodium, low urine output

D. High cortisol, high glucose

Answer: (B) High TSH, low T4

Rationale: In primary hypothyroidism, the thyroid is not making enough hormone, so T4 is low. The pituitary gland responds by increasing TSH to stimulate the thyroid 

200

Which finding is classic for Addison's disease?

A. Moon face

B. Hyperpigmentation

C. Tachycardia

D. Hypernatremia

Answer: (B) Hyperpigmentation

Rationale: Addison's disease causes low adrenal hormone levels. In primary adrenal insufficiency, ACTH rises, which can cause darkened skin or "bronzing."

200

Which lab finding is expected in SIADH?

A. High sodium

B. Low sodium

C. High potassium

D. Low calcium

Answer: (B) Low sodium

Rationale: SIADH causes excess water retention. The extra water dilutes the blood sodium, causing dilutional hyponatremia.

200

Which position is commonly used after thyroidectomy?

A. Flat with neck hyperextended 

B. Semi-Fowler's with head and neck supported

C. Prone

D. Trendelenburg 

Answer: (B) Semi-Fowler's with head and neck supported

Rationale: Semi-Fowler's helps reduce swelling and supports breathing. The neck should be supported to avoid tension on the incision. 

200

Which medication treat hyperthyroidism by reducing thyroid hormone production?

A. Levothyroxine and insulin

B. Methimazole and PTU

C. Hydrocortisone and prednisone

D. Metformin and glipizide

Answer: (B) Methimazole and PTU

Rationale: Methimazole and PTU are antithyroid drugs, They decrease thyroid hormone production, helping treat hyperthyroidism.

300

After thyroidectomy, which finding indicates hypocalcemia?

A. Hypertension

B. Tingling around mouth and muscle cramps

C. Hyperglycemia

D. Dry skin

Answer: (B) Tingling around mouth and muscle cramps

Rationale: The parathyroid glands can be affected during thyroid surgery. Low calcium causes neuromuscular irritability, including tingling, cramps, tetany, and seizures. 

300

Which electrolyte imbalance is expected in Addison's disease?

A. Hypernatremia

B. Hypokalemia

C. Hyponatremia and Hyperkalemia

D. Hypercalcemia

Answer: (C) Hyponatremia and Hyperkalemia

Rationale: Low aldosterone causes the body to lose sodium and retain potassium, so sodium drops and potassium rises. 

300

What is the priority treatment for SIADH?

A. Increase fluids

B. Fluid restriction

C. Give insulin

D. Give potassium 

Answer: (B) Fluid restriction

Rationale: SIADH means the body is retaining too much water. Restricting fluids helps reduce dilutional hyponatremia and prevents worsening neurologic symptoms.

300

After hypophysectomy, which action should the patient avoid?

A. Drinking fluid as allowed

B. Reporting clear nasal drainage

C. Blowing the nose

D. Keeping the head elevated

Answer: (C) Blowing the nose

Rationale: Blowing the nose increases pressure and can disrupt the surgical site, especially after a transsphenoidal hypophysectomy. 

300

A patient taking methimazole reports fever and sore throat. What is the nurse concerned about?

A. Hypoglycemia

B. Agranulocytosis/infection risk

C. Fluid overload

D. Hypercalcemia

Answer: (B) Agranulocytosis/infection risk

Rationale: Antithyroid medications can rarely suppress white blood cells. Fever and sore throat may signal infection and need prompt follow up.

400

Which is the priority complication after thyroid surgery?

A. Mild nausea

B. Airway obstruction

C. Constipation

D. Fatigue

Answer: (B) Airway obstruction

Rationale: After thyroid surgery, swelling, bleeding, or laryngeal nerve damage can compromise the airway. Airway is always the priority.

400

A patient with adrenal crisis needs which priority medication?

A. Levothyroxine

B. Insulin

C. IV Hydrocortisone

D. Methimazole

Answer: (C) IV Hydrocortisone

Rationale: Adrenal crisis is a life-threatening cortisol deficiency. IV hydrocortisone replaces the missing cortisol and helps support blood pressure and stress response. 

400

After hypophysectomy, what indicates possible complications?

A. Mild headache

B. Clear drainage from nose

C. Increased appetite

D. Constipation

Answer: (B) Clear drainage from nose

Rationale: Clear nasal drainage after hypophysectomy may indicate a cerebrospinal fluid leak, which increases risk for infection or meningitis.

400

After adrenalectomy, what complication should the nurse monitor for?

A. Adrenal insufficiency

B. Thyroid storm only

C. Retinopathy

D. Hypoglycemia from too much insulin only

Answer: (A) Adrenal insufficiency

Rationale: Removing adrenal tissue can reduce cortisol production. The patient may need corticosteroid replacement and monitoring for hypotension, weakness, and electrolyte/glucose changes. 

400

Which medication is commonly used to reduce tachycardia and tremors in hyperthyroidism?

A. Beta blocker

B. Metformin

C. Glipizide

D. Desmopressin

Answer: (A) Beta blocker

Rationale: Beta blockers do not cure hyperthyroidism, but they control sympathetic symptoms like tachycardia, palpitations, anxiety, and tremors. 

500

Which condition is a life-threatening exaggeration of hyperthyroidism?

A. Myxedema coma

B. Thyroid storm

C. SIADH

D. DI

Answer: (B) Thyroid storm

Rationale: Thyroid storm is severe, uncontrolled hyperthyroidism with fever, severe tachycardia, agitation, GI symptoms, and possible cardiovascular collapse. 

500

Why should corticosteroids not be stopped abruptly?

A. Causes thyroid storm

B. Causes adrenal crisis

C. Causes DKA

D. Causes SIADH

Answer: (B) Causes adrenal crisis

Rationale: Long-term corticosteroids suppress the adrenal glands. Stopping suddenly can leave the body without enough cortisol, causing adrenal crisis. 

500

Acromegaly is caused by excess of which hormone?

A. ADH

B. Cortisol

C. Growth hormone

D. Thyroid hormone

Answer: (C) Growth hormone

Rationale: Acromegaly occurs when excess growth hormone happens after the growth plates close, causing enlarged hands, feet, facial bones, and soft tissues. 

500

Which finding after thyroidectomy requires immediate follow-up?

A. Mild incision discomfort

B. Slight sore throat

C. Frequent swallowing and swelling at the neck

D. Requesting ice chips

Answer: (C) Frequent swallowing and swelling at the neck

Rationale: Frequent swallowing can indicate bleeding, and neck swelling can threaten the airway. This needs immediate assessment.

500

A patient on a long-term corticosteroids should be taught to do what?

A. Stop the medication when symptoms improve

B. Take extra doses whenever tired

C. Taper only as prescribed

D. Avoid reporting infection symptoms 

Answer: (C) Taper only as prescribed

Rationale: Corticosteroids must be tapered to allow adrenal function to recover and prevent adrenal crisis.

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