Polio Basics
What type of virus is polio
naked, positive-sense single-stranded RNA virus
Which route is the primary transmission method for poliovirus?
Fecal-oral route
Which vaccine eliminates the risk of vaccine-associated paralytic poliomyelitis?”
Inactivated Poliovirus Vaccine (IPV)
Through which receptor does the poliovirus initiate infection?
CD155 (Poliovirus receptor)
Which vaccine carries a risk of vaccine-associated paralytic poliomyelitis (VAPP)?
OPV
how many serotypes of wild poliovirus exists
three
What are the Serious Symptoms of Polio
Meningitis, Paralysis or weakness in the arms, legs, or both
What are the two types of vaccines used to combat polio?
IPV (Inactivated Poliovirus Vaccine) and OPV (Oral Polio Vaccine).
Name one key site where the poliovirus multiplies after entering the body.
Tonsils, lymph nodes, Peyer’s patches, or small intestine
What is the only known reservoir for the poliovirus?
humans
what is the meaning of the greek word polio
grey
What type of cells does poliovirus target in the CNS?
Motor Neurons
Name one non-vaccine strategy to prevent polio transmission.
Provision of clean water, improved sanitation, or better hygiene practices
What happens when poliovirus crosses into the central nervous system?
It replicates in motor neurons, causing paralysis.
What is the name of the man who lived the longest in an iron lung
Paul Alexander