You have a patient weighing 150 pounds. What is their body weight in kilograms?
What is 68.1 kgs?
This oral anticoagulant must be taken with food to ensure proper absorption.
What is rivaroxaban (≥15 mg dose)?
This class of drugs is contraindicated with nitrates due to severe hypotension.
What is PDE-5 inhibitors?
This vasopressor is a pure alpha agonist that increases systemic vascular resistance (SVR) without increasing heart rate.
What is phenylephrine?
Following a STEMI, high-intensity statin therapy should be initiated unless contraindicated. Name all high-intensity statin options (drug, dose, frequency).
What are atorvastatin 40–80 mg QD or rosuvastatin 20–40 mg QD?
The hospital has potassium chloride 20 mEq/100 mL premixed bags for K replacement. The max infusion rate is 10 mEq potassium chloride per hour. How many milliliters per hour will the nurse program the IV infusion device?
What is 50 mL/hr?
In pregnancy, this anticoagulant is preferred for the prevention and treatment of VTE during pregnancy.
What is low-molecular-weight heparin (LMWH)?
Administration of these two classes of antibiotics must be separated by multivalent cations (calcium, mag, iron, etc) due to chelation.
What is fluoroquinolones and tetracyclines?
These two vasopressors are mixed alpha/beta agonists, causing both an increase in SVR as well as cardiac output and heart rate.
What is epinephrine and norepinephrine?
In heart failure with reduced ejection fraction (HFrEF), this combination of medications replaces an ACE inhibitor or ARB to improve morbidity and mortality.
What is sacubitril/valsartan (Entresto)?
A patient with terminal cancer has morphine sulfate ordered at a rate of 4 milligrams per hour. The morphine sulfate has a concentration of 50 mg/100 mL. At what rate in milliliters per hour should the nurse infuse the morphine?
What is 8 mL/hr?
This condition is a contraindication to DOAC use due to lack of evidence and increased thrombotic risk.
What is mechanical heart valve replacement?
Omeprazole should be avoided with this antiplatelet agent.
What is clopidogrel?
This vasopressor is a natural precursor to norepinephrine and is recommended for use in patients with symptomatic bradycardia.
What is dopamine?
For a patient presenting with a STEMI, the goal door-to-balloon time for PCI is within this many minutes.
What is 90 minutes?
A pediatric patient has come into the ER with a fever. The patient weights 44 pounds. The MD orders acetaminophen (32 mg/mL) oral liquid 15 mg/kg x1 dose. What dose and volume should the patient receive?
What is 300 mg = 9.4 mL?
For treatment of a new deep vein thrombosis (DVT), warfarin and a parenteral anticoagulant should overlap for at least this many days (and until INR is therapeutic for 24-48 hours)?
What is 5 days?
Combining valproic acid with this antibiotic class can lead to subtherapeutic valproic acid levels.
What is carbapenem antibiotics? Mechanism is increased glucuronidation and clearance of valproic acid.
This inotrope is a beta-1 agonist with weak beta-2 and alpha-1 agonist activity.
What is dobutamine?
For patients with HFrEF, these four medication classes form the foundation of guideline-directed medical therapy (GDMT).
What are beta-blockers, ACE inhibitors/ARBs/ARNIs, SGLT2 inhibitors and mineralocorticoid receptor antagonists (MRAs)?
A patient requires heparin 18 units/kg/hour. The bag contains 25,000 units in 500 mL D5W, and the patient weighs 70 kg. What is the infusion rate in mL/hour?
What is 22.7 mL/hour?
In a patient with life-threatening bleeding from warfarin and elevated INR, this product can be used for rapid reversal.
What is 4-factor prothrombin complex concentrate (PCC, Kcentra)? Given in combination with intravenous vitamin K.
Name a medication that DOACs should not be used in combination with due to decreased effectiveness of the DOAC due to increased metabolism.
What is strong CYP3A4 inducers? Rifampin, phenytoin, phenobarbital, carbamazepine
This inotrope is a PDE-3 inhibitor in cardiac and vascular tissue.
What is milrinone?
This P2Y12 inhibitor requires a dose adjustment in patients weighing < 60 kgs and/or >/= 75 years of age.
What is prasugrel?