ROCKET AF
The mean CHADS2 score and median age of patients in ROCKET AF.
What is 3.5 and 70 years old?
Pts were Risk Stratified by these two methods in a Post Hoc Analysis of Compass.
What is Reach & CART
The phone number pt's should call for Janssen Select.
What is 1-888-XARELTO?
Xarelto's most common adverse reaction (>5%).
What is bleeding?
The name of Libby's dog.
Who is Brooklyn?
The % of patients in the ROCKET AF trial that had obesity with a BMI >30 kg/m and % that had BMI > 35 kg/m.
What is 37% and 13%?
The Major Bleed percentages with Xarelto 2.5mg BID + ASA vs. ASA alone.
What is 1.6% for Xarelto + ASA vs. .9% for ASA alone?
The cost of Xarelto under Janssen Select.
What is $200/year OOP and then $85/month?
The indications for Xarelto.
What is NVAF, Tx PE, Tx DVT, Recurrent DVT or PE, Prophylaxis of DVT/PE, pts undergoing knee or hip replacement surgery, Prophylaxis of VTE in acutely ill, to reduce the risk of major CV events in pt's with chronic CAD/PAD?
Libby's favorite alcoholic beverage.
What is red wine?
In ROCKET AF trial the % of risk reduction in Stroke/SE in Intent to Treat population and the % of risk reduction in the Safety as-treated population and which population achieved superiority.
What is 12% in ITT population, 21% in the Safety as-treated population and Xarelto is superior to warfarin in the Safety as-treated population?
Describe 4 ways a PAD patient can present (from Veeva Asset).
What is Intermittent Claudication, Previous Limb/Foot Amputation, Carotid Artery Stenosis and Revascularizing Intervention?
Once pt's hit coverage gap what % do they pay for Xarelto.
What is 25% retail cost?
Xarelto contraindications.
What is active pathological bleeding, & Severe hypersensitivity reaction to Xarelto?
Libby's favorite thing to bake.
What is bread?
PK/PD measures that are used to determine consistent drug levels.
What is C max, AUC and Anti-factor Xa activity?
Describe the European Guideline Recommendations/Including which class & level.
What is Antithrombotic therapy for people with Chronic Coronary Syndromes & in Sinus Rhythm. Level 2a- Class A in patients at high risk of Ischemic Events and without high bleeding risk. Level 2b-Class A in patients at moderate risk of ischemic events without high bleeding risk?
JJPAF eligibility.
What is pt has no RX coverage and/or pt pays 4% of annual income towards their medications?
Dose adjustment needed based on CrCl in pt's with CAD/PAD.
What is no dose adjustment needed?
The names of Libby's children.
Who is Chase and Connor?
In a Real-World Study (Veeva asset) vs. warfarin, the rates of Stroke/SE in patients who have NVAF and morbid obesity.
What is 1.5% in patients taking Xarelto vs. 1.7% in patients taking Warfarin? (Comparable reduction rates)
State MACE & MALE Categories and % Reductions.
What is MACE: 24% RRR, CV Death 22%RRR, MI 14 % RRR, and Stroke 42% RRR?
What is MALE: 28% RRR, Acute Limb Ischemia 44% RRR, Lower Extremity Amputation 52% RRR, and All Cause Mortality 18% RRR?
Doses that are eligible to use for the $10 copay card.
What are 2.5mg, 15mg & 20mg?
For the 2.5mg BID dose, 10mg & 20 mg dose in a fasted state, the absolute bioavailabilty of Xarelto is approx.______________.
What is 80-100% for 2.5mg BID & 10mg and 66% for 20mg dose?
The University Libby graduated from.
What is Miami University?