Safety
QC
Miscellaneous
Anemias
WBC Disorders
100
The three components of WHMIS
Labels, SDS, Worker Education/Training
100
This is better than the standard of deviation for describing precision
Coefficient of variation (CV)
100
In a patient with G6PD deficiency, they are unable to reduce this compound which results in oxidative stress
glutathione
100
Hemoglobinemia and hemoglobinuria are common findings of which mechanism of anemia
Intravascular Hemolysis
100
This results from a recessive trait mutation that causes mucopolysaccharide storage problems in white blood cells
Alder-Reilly Anomaly
200
This pictogram includes germ cell mutagenicity, respiratory or skin sensitization, and aspiration hazards, among others
Health Hazard
200
When the computer compares a patient’s current test results to their most recent result
Delta check
200
Give two common characteristics of all maturing blood cells
- reduces in size
- condensed chromatin
- loss of nucleoli
200
The enzyme deficiency in Sideroblastic anemia
ALA Synthase (vitamin B6 can exacerbate the condition)
200
A five-year old boy’s CBCD showed an abundance of this type of cell. These cells are
Reactive lymphs
300
The acronym that helps to stop fires
PASS (pull pin, aim at base, squeeze nozzle, sweep from side to side)
300
This algorithm is an additional quality control check installed in instruments to monitor red cell indices, as they have been shown to remain relatively stable over time for a given population
Bull’s Moving Averages
300
What are trephine biopsies used for?
If there is a dry tap -- must use this to assess cellularity and structure of marrow. NEVER used for a differential
300
The process of making this nucleic acid is absent or defective in this macrocytic form of anemia
Thymine; megaloblastic anemia
300
A man in his fifties was recently diagnosed with leukemia. His immunophenotyping results are as follows: CD2-, CD3-, CD10+, CD11c+, CD19+, CD20++, CD22+, CD34+, CD103+, Tdt+. His doctor diagnosed him with
Hairy Cell Leukemia
400
The best type of control in the hierarchy of controls
Engineering controls
400
The three components of a good QC material
Similar in composition to the unknown sample, it must be analyzed in the same manner, and stable
400
GPI is a molecule which gets incorporated into the lipid bilayer. Which disorder causes the absence of GPI molecules (please list them)
Paroxysmal nocturnal hemoglobinuria; GPI 55,59
400
This occurs when all four alpha chains in the Hb gene are deleted
Hb Bart’s
400
A 23-year-old athlete suspected of “doping” was under investigation. His CBCD showed abnormally elevated RBC counts independent of EPO levels. His WBC and PLT counts also appeared to be elevated. His condition is
Primary Polycythemia Vera
500
The components of the fire triangle
Heat, fuel, oxygen
500
Upon reviewing the biweekly QC reports, the tech II noted this error in their Level II Sysmex Controls
What is R-4s
500
This "factor" is implicated in both Atypical HUS and TTP
Von Willebrand Factor
it is readily released from damaged endothelial cells and promotes platelet adhesion; leads to large multimeters of vWF in circulation although ADAMTS-13 protease activity is normal in HUS patients
500
Individuals with sickle cell trait or sickle cell anemia may have normal red blood cells in circulation. Sickling of the cells occurs when… (Name 3 conditions)
Low O2
Low pH
Increased [2,3-BPG]
Cell dehydration
500
A patient presented with a multitude of these types of cells in his PBS. What does he likely have? Be specific.
AML