Optia
Disease Processes
Plasma Exchange
Stem Cell Collections
Photopheresis
100

The anticoagulant commonly used to prime the Optia machines.

What is Anticoagulant Citrate Dextrose?

100

Usual approach is to perform daily exchanges until patient is neurologically normal, plt count of 150k or greater and LDH has dropped to normal or near normal.

What is Thrombotic Thrombocytopenic Purpura?

100

The standard fluid replacement for a patient with Thrombotic Thrombocytopenic Purpura?

What is 100% FFP?

100

The hematologic malignancy with risk of Leukostasis

What is acute leukemia

100

For patients who require ECP but have a contraindications to heparin, this agent is a safe alternative 

 

What is acid citrate dextrose (ACD-A) ? 

200
In this fluid balance, patient is usually left positive 245 ml without a Calcium gtt (-150 Chamber Fill + 345 Rinseback + 50 Bloodwarmer flush = 245ml).
What is 100% fluid balance?
200

Autoimmune disease characterized by presence of antibody to acetylcholine receptor on motor end place.

What is Myasthenia Gravis?

200
The default AC infusion rate fo all TPE procedures and a warning appears if AC infusion rate exceeds this rate.
What are 0.8ml/min/L of TBV and 1.2 ml/min/L of TBV.
200

The minimum CD34 count for a rapid and sustained hematopoietic recovery after an autologous stem cell tranpslant

What is 2 million 


200

Photopheresis is most commonly used to treat  this condition and graft-versus-host disease GVHD

What is cutaneous T cell lymphoma?

300

The lowest flow rate for a patient.

What is ml/min?

300

The treatment for steroid-resistant, steroid-intolerant, or steroid-dependent chronic GVHD

What is Extra-Corporeal Photopheresis 

300

The most common adverse event associate with TPE

What is hypocalcemia? 

300

The mobilization agent that is only effective with the use of growth factors

What is plerixafor

300

ECP involves collection of buffy coat from whole blood, treatment with this agent instilled in the collection bag and exposed to UV light

What is 8-methoxypsoralen? 

400

Calcium gluconate gtt is running at 120ml/hr after a patient complaint of perioral tingling once. The flow rate of this leukapheresis is expected to be at what speed?

What is 100ml/min?

400
Rare diseases that are commonly treated with plasma exchange which could manifest as respiratory failure secondary to hemoptysis and acute renal failure.
What are Goodpasture's syndrome and Wegener's Granulomatosis?
400

The time it takes for coagulation parameters to normalizes when albumin is the replacement fluid

What is 24 to 72 hours? 

400

What is a rare but fatal risk of G-CSF?

What is splenic rupture

400

ECP is FDA approved for this condition


What is Cutaneous T-cell Lymphoma?

500

In manual rinseback, the following valves are in what positions: Waste Divert, Return Line, RBC/Plasma Line, Plasma/RBC and Collect/Replace.

What are Closed, Open, Open, Return and Collect.

500
Results from a combination of increased concentration and asymmetric shape of the IgM molecule. Symptoms usually occur when monoclonal IgM concentration exceeds 3.0 g/dl.
What is Hyperviscosity Syndrome/Waldenstrom's Macroglobulinemia.
500

The percentage of grade 4 (fatal) event related to the TPE procedure

What is less than 1%? 

500

Hematopoietic stem cell source are peripheral blood, bone marrow and..

What is Umbilical cord

500

This serious blood condition can be related to frequent heparin exposure in ECP

What is Heparin Induced Thrombocytopenia (HIT)? 

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