Apheresis Basics
TPE/RBCx
Cellular Therapy
Photopheresis
Challenge
100

Apheresis procedures are often confused with dialysis; however, the main difference is that dialysis does this.

What is the cleaning of waste from the blood. 

100

The main difference between TPE and RBC exchange is which component is removed.

What is plasma versus red blood cells?

100

Cellular therapy procedures commonly collect these specific type of cells.

What are stem cells? (Also acceptable - T cells)

100

This treatment uses what kind of light exposure to modify collected cells.

What is ultraviolet (UV) light?

100

Therapeutic apheresis is considered medically necessary because it directly affects this.

What is patient health?

200

This separation method is commonly used in therapeutic apheresis machines.

What is centrifugation?

200

This replacement fluid is commonly used during plasma exchange.

What is FFP and/or Albumin?

200

This type of transplant uses cells collected from a donor that are then given to a recipient. 

What is an allogeneic transplant?

200

Photopheresis is commonly used to manage this transplant-related complication.

What is graft-versus-host disease (GVHD)?

200

This common thread links our TPE, RBCx, & cellular therapy procedures, but not photopheresis.

What is the Spectra Optia?

300

Apheresis procedures rely on this physical property to separate blood components in the centrifuge.

What is density?

300

RBC exchange is often used to reduce complications in patients with this inherited condition.

What is sickle cell disease?

300

This type of transplant uses the patient’s own collected cells.

What is an Autologous transplant?

300

Photopheresis treats disease by influencing this system rather than replacing components.

What is the immune system?

300

LDL apheresis is a treatment used to lower this substance in the blood.

What is cholesterol?

400

This factor primarily determines how long an apheresis treatment will last.

What is the patient’s total blood volume and treatment prescription?

400

This is the primary risk if fluid or replacement calculations are incorrect during TPE or RBCX.

What is adverse reaction?

400

What makes cellular therapy different from all other apheresis procedures.

What is long‑term use of collected cells?

400

Why missed or irregular photopheresis sessions reduce effectiveness.

What is loss of cumulative treatment effect?

400

What makes apheresis a process rather than a single event.

What is continuous separation, monitoring, and return?

500

How therapeutic apheresis differs from donor apheresis.

What is treating patients instead of collecting components?

500

Why RBC exchange focuses on replacement, not removal alone.

What is maintaining oxygen‑carrying capacity?

500

What makes mobilization timing a critical factor in stem cell collection.

What is peak cell availability in the bloodstream?

500

What makes photopheresis unique compared to TPE or RBCX.

What is treating cells outside the body and returning them?

500

This single concept best explains why therapeutic apheresis cannot be treated like a standard donor operation.

What is patient‑specific, medically necessary care?

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