Testoster-zone
(All things Male)
(All things Male)
Estrogen Session
(All things Female)
(All things Female)
Girls run the world
(All things Female PT2)
(All things Female PT2)
Goiters: Pros and Cons
"It's got bones in it!"
Wild Card!!!
100
Which drug is used for treatment of ED and BPH symptom relief?
Tadalafil
100
What is the name of the Progestin Only Pill that offers a 24-hr missed dose window?
Slynd
Other minipill options have a missed dose window of ~3-hrs
100
Contraceptive patches have increased reports of what adverse effect?
Thromboembolism; Slides say up to a 60% in estrogen exposure.
<24 hours of detachment = reattach. >24 hours = backup contraception for 7 days
100
Elevated ________ is a laboratory sign for Hyperthyroidism.
T3 & T4
The Hyper- and Hypo- is directly related to T3 and T4.
100
What are the two clinically relevant thresholds for a T-score and what diagnosis correlates with each score?
100
Name a nonstimulant medication for treatment of ADHD.
Atomoxetine(Strattera), Guanfacine(Intuniv), Clonidine(Kapvay), Viloxazine(Qelbree)
200
The AUASI questionnaire has patients rate 0-5 on these seven urination habits that may be present in BPH. Name 2+ of these habits for points.
200
Describe the Yuzpe method in your own words.
[Slide 61]
200
Excess Estrogen and Progestin Deficiency share these two Adverse Effects.
Dysmenorrhea & Menorrhagia
[Contraception: Slides 67 & 68]
200
Name the medication treatment that supplements a patients T3 levels (only).
Liothyronine = T3
Levothyroxine = T4
Liotrix = 4:1 of T4:T3
200
What is the unique risk associated with 5+ years of oral bisphosphonate use?
Increased risk of atypical fracture.
(IV bisphosphonate use the risk is achieved sooner at 3 years)
200
When treating Addison's disease, how should the dose be distributed?
2/3 in the morning, and 1/3 in the evening
*Mimics the normal adrenal rhythm*
300
What is the criteria for diagnosing Male Hypogonadism?
Requires: Symptoms AND two separate testosterone test of <300ng/dL
Test conditions: First thing in the morning, and ideally separated by 4 weeks
300
What is the purpose of using spironolactone in PMS management?
Management of bloating, fluid retention, and breast tenderness during luteal phase.
300
Match the following names with their timeframe:
A. Jolessa 1. Non-cyclic
B. Amethyst 2. 91-day regimen
C. Camrese 3. 84-day regimen
A=3; Jolessa is 84-day with 7 inactive days
B=1; Amethyst is non-cyclic and offers no withdrawal bleeding
C=2; Camrese is 91-day of continuous estrogen
300
A 30 year old Female weighing 176 lbs standing 5'10" tall needs a starting dose of Levothyroxine to combat her hypothyroidism. What is her dose?
What is her dose if she was pregnant?
IBW = 45.50 + (10*2.3) = 68.50
68.5*1.6 = 109.6(mcg)/(day)
Round up to nearest medication amount: 112mcg
Pregnancy variation is 30-50% increase:~142-164mcg; Rounded to 150-175mcg
300
What are the three conditions where a patient would receive OP Treatment?
Follow up: At what values would a patient be considered very high risk?
1. Non-traumatic hip or vertebral fracture
2. T-score <-2.5
3. T-score between -1 & -2.5 with either of the High Risk FRAX score values.
High Risk: >3% Hip fracture & >20% Maj. OP fracture
Very High Risk:
- >4.5% Hip fracture OR >30% Maj. OP fracture
- T-score <-3.0
- T-score -2.5 to -2.9 W/ recent fracture while on approved OP therapy
300
What are some of the manifestations of Cushing's Syndrome?
Fat distribution: Buffalo hump, or Supraclavicular fat pads
Skin changes: facial plethora, hirsutism, and striae
400
Which of the following drugs could produce urinary hesitancy or cause outflow obstruction?
- Amitriptyline
- Nasal phenylephrine
- Advair Diskus
- Olanzapine
All of them!
- Amitriptyline (TCA)
- Nasal phenylephrine (Oral/Nasal Decongestant)
- Advair Diskus (LABA)
- Olanzapine (Antipsychotic)
400
Women affected by infertility caused by PCOS can use which two drugs to induce Ovulation?
Letrozole or clomiphine
400
Name a contraceptive that would be appropriate in an obese woman not wanting any more weight gain.
Non-Weight Gain: Copper IUD
Weight Gain: Depo-Provera, Nexplanon, Any progestin containing contraceptive
400
What medication is used at 100mg q8h to rule out coexisting adrenal suppression in the case of a Myxedema Coma?
Hydrocortisone.
Myxedema coma is the extreme case of hypothyroidism, and can often be hard to find due to symptoms developing slowly.
400
After how many years of annual Zoledronic Acid injections should a holiday be considered?
Zoledronic Acid: 3 yrs in High risk or until fracture risk is no longer high; This is increased to 6 years in Very high risk patients.
400
Provide a ratio of Prednisone:Hydrocortisone in terms of equivalent Potency.
1:4
5mg Pred ~ 20mg Hydrocortisone
[Adrenal gland Disorder; Slide 44]
500
In your own words, explain Nitrates and how they have DDI with PDE-5 inhibitors
500
The ACHES acronym represents adverse effects that patients should be aware of when taking contraception. match one of the letters with AE and what concerns it is paired with.
Popcorn to next person after you provide one example.
500
A patient wants to switch from their nexplanon implant to a combination oral contraceptive. What is the timing of taking the new COC with the removal of the implant to ensure no loss in contraceptive coverage?
7 days prior to removal.
[She has a few interesting documents on the contraceptives module with various charts and such on missed doses, switching, etc. I would take a look]
500
Name the drug that can cause both hypo and hyperthyroidism. And list the monitoring parameters for it.
Amiodarone.
Measuring baseline TSH prior to use. Additionally, required monitoring every 6 months.
500
Describe the MOA of Denosumab.
Bonus points: It is also indicated for use in patients with two types of cancers undergoing specific therapy. What are the two types of cancers?
MOA: Reduced Osteoclast function & Reduced Osteoclastogenesis
Cancers:
- Female: Breast cancer w/ Aromatase inhib therapy
- Male: Prostate cancer w/ gonadotropin-reducing hormone therapy
500
Name the emergency kit that should be provided to all Addison's disease patients for use in an Addisonian crisis.
Glucocorticoid or Solucortef