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Topic 2
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100

A type of interaction between molecules, specifically their surfaces, where there is no sharing of electrons.

What are van der Walls attractions?

100

This amino acid prefers a cis configuration when in a peptide bond.

 What is Proline?        

100

Proteins selectively bind to their respective ligands with high affinity using these types of bonds.

What are weak noncovalent bonds? (Hydrogen bonds, electrostatic attractions, van der Waals attractions, & hydrophobic interactions)

200

This contains hydrophobic and hydrophilic elements and will form spontaneously when these elements are suspended in water.  

What is a phospholipid bilayer?

200

These bonds allow for rotation in the peptide backbone. 

What are phi and psi bonds?

200

To identify specific sites within proteins that signify the protein domain’s overall functionality, this method is likely used to evaluate such sequence comparisons.

What is evolutionary tracing?

300

The smallest segment of the tree of life, which contains subcellular organelles and is believed to have evolved later from a pre-existing life form.

What are Eukaryotes?

300

This secondary structure is ideal for membrane channels.

What is an Amphiphilic Alpha Helix?

300

In enzyme kinetics, this is a measure that determines how tight the substrate is bound, with larger values correlating to weaker binding.

What is Km?

400

 A method of gene evolution that occurs within the same organism, and results in a hybrid gene due to two or more genes breaking and rearranging.

What is DNA segment shuffling?

400

A structural unit that folds independently from the rest of the protein and provides a specific function.

What is a domain?

400

The component found in an alpha helix that binds to another domain within the same protein molecule, serving to hold the protein in a “closed” conformation, then becoming released after GTP hydrolysis.

What is the switch helix?

500

Reactions are said to be this, where there is an increase in disorder and the reaction is energetically favorable.

What is spontaneous?

500

One advantage of having protein subunits.

What is requires a small amount of genetic information, controlled assembly and disassembly, or reduces synthesis error rate?

500

This category of proteins function in linking sets of activating, inhibiting, adaptor, and substrate proteins at a specific location within a cell.

What are scaffold proteins?

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