Why Change
This percentage range of U.S. adults on antihypertensive therapy still have uncontrolled blood pressure despite multiple prescriptions.
What is 10–30%
Guidelines from the AHA, ISH, and ESH all say this must be ruled out before diagnosing resistant hypertension.
What is nonadherence
Mayo’s antihypertensive panel can detect this many commonly prescribed hypertension medications.
What is 16
This technology is used to detect medications in the urine.
What is liquid chromatography-tandem mass spectrometry (LC-MS/MS)
The Mayo test code for the Antihypertension Panel, Random, Urine.
What is AHPRU
This common cause of apparent resistant hypertension is often overlooked and not included in prevalence stats.
What is medication nonadherence
This percentage of patients with apparent resistant hypertension were nonadherent in some studies.
What is 37%
This number of commonly available diuretics are detected by the test.
What is five
The panel assesses whether a patient has taken their medication within this time frame.
What is the previous 24 hours
Specimens for the test should be kept in one of these conditions.
What is refrigerated or frozen
Cases labeled as "resistant hypertension" are often not truly resistant but driven by this.
What is patients not taking their medication
Indirect adherence methods like self-report identify only this percentage of nonadherent patients.
What is 20%
One costly procedure that could be avoided by early adherence testing.
What is adrenal vein sampling
This type of sample is used for the test.
What is a random urine sample
The test is performed on this day of the week.
What is Friday
Instead of being rare, this condition affects up to 3 in 10 patients on antihypertensives.
What is treatment resistance
LC-MS/MS urine testing can uncover nonadherence in this much higher percentage of patients.
What is 46%
Avoiding unnecessary specialist referrals and imaging saves this range in dollars.
What is $5,000–$10,000
The test can help avoid this time-consuming and expensive adherence check method.
What is directly observed therapy
This type of hypertension medication is excreted in urine and can be detected in testing.
What is antihypertensive medications
This national network has noticed increasing cases of uncontrolled blood pressure despite treatment.
What is the Mayo Clinic reference network
Discussing biochemical test results with patients can reduce systolic blood pressure by this average amount.
What is 20 mm Hg
This exclusive feature sets Mayo’s antihypertension urine panel apart from other labs.
What is no other laboratory performs it
The test can return results in this time range.
What is 2–9 days
In addition to detecting diuretics, the test comprehensively assesses these.
What are anti-hypertensive medications