Combination therapy with peg interferon and ribavirin, including boceprevir and telaprevir
What is triple therapy?
100
The HCV virus can progressively result in hepatic injury, hepatic fibrosis and liver cirrhosis and is transmitted by this form of contact
What is blood and blood products?
100
This is a way for nurses to help reduce the spread of HCV infection in patients
What is teaching the patient about proper sterilization of needles?
100
This causes itching
What is pruritus?
200
The major cause of liver disease
What is infection of hepatitis C?
200
This goal becomes the focus for patients who don't respond to treatment
What is limiting fibrosis progression
200
These factors play a role in the increased development of the HCV virus
What is older age, male gender, excessive alcohol intake, co-infection with hepatitis B & HIV, or immunosuppression related to organ transplantation?
200
This is the gold standard for assessing disease activity and severity in patients with chronic HCV
What is percutaneous liver biopsy?
200
To be treated with antihistamines, topical steroids, and avoidance of sun exposure
What is a rash?
300
These two 3/4 A protease inhibitor drugs aid in triple therapy for HCV
What are telaprevir and boceprevir?
300
Reasons triple therapy is beneficial
What are increased percentage of response to treatment, endurance of elimination of HCV RNA from their serum, and receiving an overall improved quality of life?
300
These people are hard to treat with triple therapy
What are cirrhosis patients and African-Americans?
300
This is the most common histologic feature nurses should look for in patients with chronic HCV
What is fatty liver, also known as steatosis?
300
Anemia
What is an adverse effect of triple therapy?
400
The most significant result of chronic infection of HCV
What is the evolution of hepatic fibrosis?
400
These are compounds developed with anti-viral activity against HCV genotype I
What are DAA's (direct acting antiviral agents)?
400
A person's genotype determines this
What is sustained virologic response?
400
This is the dose of telaprevir to be given for a HCV patient
What is 750 mg TID for 12 weeks
400
These two are side effects that most drugs cause
What are nausea and diarrhea?
500
The primary goal for treatment
What is the eradication of the virus?
500
This is the single most important predictor of treatment response
What is HCV genotype?
500
These factors have a small amount of relation to the variability in the development of HCV?
What is environmental?
500
Nurses should make sure that triple therapy is taken with this type of food