ASD
An adult patient with pulmonary tuberculosis will be given isoniazid. The patient is currently taking carbamazepine for focal seizure to bilateral tonic-clonic seizures. Which of the following will be the expected effect?
A) Rate of metabolism of isoniazid will be decreased
B) Clearance of carbamazepine will be reduced.
C) Excretion of isoniazid will be enhanced
D) Plasma concentration of carbamazepine will increase
D. Plasma concentration of carbamazepine will increase
A person is addicted to a very expensive oral drug which induces feelings of friendliness, euphoria, hyperactivity. When under the influence the person is also noted to drinking lots of water. After sometime, this person is checked into a rehab clinic wherein withdrawal symptoms of depression manifests. The MOST likely agent is:
A) Nicotine
B) Ecstasy
C) Morphine
D) Cannabis
B. Ecstasy
A patient diagnosed with biliary obstruction is complaining of annoying pruritus which disturbs his sleep. He was told that this is due to his condition. Which of the following may help this patient?
A) Colestipol
B) Gemfibrozil
C) Niacin
D) Simvastatin
A. Colestipol
Which drug is indicated for acute gout and
prophylaxis between attacks, binding to
intracellular protein tubulin?
a. Allopurinol
b. Febuxostat
c. Colchicine
d. Pegloticase
C. Colchicine
This inhaled anesthetic is typically used as a carrier of other agents, has a high MAC, rapid onset and recovery, and is colloquially known as “Laughing Gas”
a. Nitrous Oxide
b. Desflurane
c. Halothane
d. Isoflurane
A. Nitrous Oxide
Which anti-epileptic medication has elevated risk of teratogenesis?
A. Lacosamide
B. Phenytoin
C. Levetiracetam
D. Lamotrigine
D. Lamotrigine
A 36-year old, male, substance abuser develops withdrawal symptoms of sleep disturbances, irritability, phonophobia, photophobia, cramps and depression after sudden cessation of taking the drug. Which agent was initially abused, causing him the above said symptoms?
a. Flumazenil
b. Benzodiazepine
c. Amphetamine
d. Nicotine
B. Benzodiazepine
A 30 year old pregnant patient was diagnosed with peptic ulcer disease. Which of the following medications is contraindicated to the patient?
a. Omeprazole
b. Misoprostol
c. Cimetidine
d. Sodium bicarbonate
B. Misoprostol
A 50 year old male patient was brought to the ER after he was found unconscious on his bed with vomit all over him. His wife reported that his husband took a handful of pills after their heated argument and found an empty bottle of pills on their bedside table. He was diagnosed with Acetaminophen toxicity. What agent will serve as an antidote?
a. Naloxone
b. N-acetylcysteine
c. Vitamin K
d. Charcoal hemoperfusion
B. N-acetylcysteine
Which Anesthetic is paired with the enzyme that metabolizes it?
A. Chloroprocaine - CYP450
B. Lidocaine - butyrylcholinesterase
C. Fospropofol - Alkaline Phosphatase
D. Nitrous Oxide - CYP450
C. Fospropofol - Alkaline Phosphatase
Identify: The patient had a continuous seizure for 6 minutes without complete recovery of consciousness. What is the appropriate first line treatment?
Diazepam
An addict was found to be smelling of vinegar, and with needle marks on his arm. He was observed to be sweating heavily, with a runny nose, and unusually dilated pupils. How long has it been since his last dose?
a. 0-8 Hours
b. 8-24 Hours
c. 1-3 Days
d. 4-7 Days
B. 8-24 Hours
An inhaled muscarinic receptor blocking drug used for asthma, causes bronchodilation and reduces pulmonary secretions. What agent are we describing?
a. Salbutamol
b. Ipratropium
c. Fluticasone
d. Theophylline
B. Ipratropium
Other than Methotrexate, this DMARD is also acts as a chemotherapeutic agent. What is its Mechanism of Action?
a. Inhibits AICAR transformylase and thymidylate synthetase
b. Mechanism is not fully understood
c. Cross Linking of DNA prevents Cell Replication
d. Small Molecule Inhibitor of Phosphodiesterase
c. Cross Linking of DNA prevents Cell Replication
Buprenorphine is a partial mu-receptor antagonist and phenanthrene derivative used for the management of opioid dependence, withdrawal and detoxification. It is a mixed receptor opioid relative to its Delta and Kappa receptor antagonistic property.
A. First statement is TRUE, Second statement is FALSE
B. First statement is FALSE, Second statement is TRUE
C. Both statements are TRUE
D. Both statements are FALSE
B. First statement is FALSE, Second statement is TRUE