General Knowledge
What is the capital of Jamaica?
Kingston
Which is the leukotriene modifier most commonly used in asthma therapy?
Montelukast (Singulair)
Four major categories of pathogens:
Viruses, bacteria, fungi, and parasites
What is the tendency of people to favor information that confirms their beliefs or values?
Confirmation bias
What enzymes are the statins famous for inhibiting?
HMG-Coenzyme reductase
What is the highest grossing video game of all time?
Minecraft
Which of the cephalosporins is known to be active against MRSA?
Ceftaroline (Teflaro)
What immunoglobulin is best known for its role in allergy and asthma?
IgE
What study design ranks the highest within evidence based medicine?
Meta-analysis
What opioid receptors does Suboxone target?
Mu and kappa receptors
In what state was Bruno Mars born and raised?
Hawaii
Which triple therapy combination is known as the ‘’triple whammy’’ for their ability to cause harm to the kidneys leading to acute kidney injury?
NSAIDS, ACEi/ARBs and diuretic
What is IgA found in?
Mucus in gut, milk, tear, and saliva
What type of statistics do nominal and ordinal data fall under?
Nonparametric statistics
Name a drug that specifically inhibits 5-alpha reductase, an isoenzyme that metabolizes testosterone into DHT
Finasteride/dutasteride
What was the last branch of the military to be added?
US Space Force
Calculate the CHADS-VASc Score:
74 y/o female with a PMH of thromboembolism, diabetes, CKD, and dementia. Her vitals and labs are WNL. She has no other known comorbidities or issues.
5
What do adjuvants do to the immune system?
Enhance immune response to a vaccine
What FDA “book” would you use to find information on biologicals?
Purple Book
Name the drug class that is known as a potent peroxisome proliferator activator gamma also known as PPAR-gamma agonist that depends on the presence of insulin for its action. It increases insulin dependent glucose disposal and decreases hepatic glucose output by decreasing insulin resistance.
Thiazolidinediones (TZD)
What is the name of the artist that painted this picture?
Salvador Dali
What medication is focused on directly inhibiting the first step of the RAAS system?
Aliskiren (Tekturna)
Name one activating pathway of the complement system.
Classical/lectin/alternative
Between JAMA, NEJM, and Lancet, which journal has the highest impact factor as of 2024?
Lancet
Name the drug class that focuses on inhibition of bacterial topoisomerase IV and DNA gyrase, enzymes needed for replication, transcription and repair of bacterial DNA.
Fluoroquinolones