Hematology 1
Most common cause of iron deficiency in men and postmenopausal women
GI blood loss
Most common cause of classic HUS
Shiga toxin–producing E. coli
Microcytosis, normal RDW, normal or increased erythrocyte count
Thalassemia
Cause of pseudothrombocytopenia
Platelet clumping
Lab finding of citrate toxicity during massive transfusion
Hypocalcemia
Initial decision support tool in evaluating low-risk PE
PERC
Evaluation of PE in patients with contraindication to IV contrast
V/Q scan
Chronic hemolytic anemia, spherocytes, negative DAT
Hereditary spherocytosis
Isolated mild asymptomatic neutropenia in a patient of African descent
Duffy-null associated neutrophil count
Confirms folate deficiency when serum folate level is normal
Elevated serum homocysteine level
Labs diagnostic of moderate/severe hemophilia A or B
Prolonged aPTT (corrects with mixing study), normal PT and CBC
Treatment of acute proximal DVT or PE when anticoagulation is contraindicated
Retrievable or temporary IVC filter
Anticoagulation for distal DVT without symptoms or risk factors for extension
None
Management of warfarin over-anticoagulation, INR >10, no bleeding
Stop warfarin, give oral vitamin K
Cold agglutinin disease treatment
Rituximab
Prolonged aPTT, low factor VIII, no correction with mixing study
Acquired hemophilia
Ineffective hematopoiesis, hypercellular marrow, peripheral cytopenia, normal vitamin B12 and folate
MDS
Skin, GI, and liver injury following allogeneic HSCT
Graft-versus-host disease
HIT therapy duration with documented thromboembolic event
At least 3 months
Management of life-threatening bleeding in patients taking oral Xa inhibitors
Four-factor PCC or andexanet alfa
Management of hemophilia A, active bleeding, high titer inhibitor
Activated factor VII
Treatment of DIC-related hypofibrinogenemia
Cryoprecipitate
MDS therapy that reduces transfusion requirements and AML conversion risk
Hypomethylating agent (azacitidine or decitabine)
5q− MDS treatment
Lenalidomide
Duration of smoking-induced neutrophilia following smoking cessation
≥1 year