Neurology
Rheumatology
Hematology
Endocrinology and Metabolism
Oncology
100

Initial treatment of convulsive status epilepticus

IV benzodiazepine or IM midazolam

100

Treatment of suspected giant cell arteritis

Immediate high-dose glucocorticoids

100

Hemoglobin transfusion threshold for most patients

<7 g/dL

100

First lab test for thyroid nodule

TSH level

100

Effective cervical cancer prevention

HPV vaccination

200

Initial treatment of ocular and mild generalized myasthenia

Pyridostigmine

200

Most specific serologic test for RA

Anti–cyclic citrullinated peptide antibody

200

Warfarin-related life-threatening bleeding treatment

Four-factor PCC

200

Initial test for suspected acromegaly

IGF-1 level

200

Genetic testing for metastatic prostate cancer

Germline variant (including BRCA) and somatic mutation testing

300

Complete myelitis, no CSF oligoclonal bands or IgG index, no brain MRI lesions

Idiopathic transverse myelitis

300

Preferred initial monotherapy for RA

Methotrexate

300

Acute promyelocytic leukemia treatment

All-trans retinoic acid and arsenic trioxide

300

Treatment of macroprolactinoma

Dopamine agonist

300

Testing for all patients with metastatic NSCLC to guide therapy

PD-L1 expression

400

Antibody test in myasthenia gravis with weakness of cervical extension

Anti–muscle-specific tyrosine kinase (MuSK)

400

Most effective maintenance therapy in granulomatosis with polyangiitis

Rituximab

400

Treatment of complement-mediated HUS

Eculizumab

400

Initial localization study of choice for primary aldosteronism

Dedicated adrenal CT

400

Molecular analysis for all metastatic colorectal cancer

KRAS, NRAS, BRAF, mismatch repair genes; HER2 amplification status

500

Management of unceasing convulsive status epilepticus after IV benzodiazepine and ASM

Intubation; anesthetically induced coma for 24-48 h (propofol, midazolam, or pentobarbital)

500

Acute severe myopathy and anti–HMG Co-A reductase antibodies

Immune-mediated necrotizing myopathy

500

Two main causes of kidney disease in MM

Hypercalcemia and cast nephropathy

500

Diagnosis suggested by hyperthyroidism, elevated TSH, and elevated free T4

TSH-secreting pituitary tumor

500

Effectiveness of current immunotherapies for mismatch repair-proficient colorectal cancers

Ineffective

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