PVCS + NSVT
Accelerated Idioventricular Rhythm
Evaluation and Management of VT
Congenital Heart Disease, and Cardiomyopathies with VT
Polymorphic VT
J Wave Syndromes and VFib
Bradyarrhythmias
AV Blocks
100

Abnormal impulse formation or reentry in the ventricular myocardium or purkinje system producting depolarization wavefront that propagates through the ventricles independent of activation from atrium or AV node

what is a PVC?

100

the mechanism of accelerated idioventricular rhythm is

What is automaticity 

100

Best initial treatment for idiopathic VT in the absence of structural heart disease

beta blockers or catheter ablation

100

In patients with HCM who have _______ or ______ an ICD is a class I recommendation if meaningful survival is greater than 1 year. 

Sudden Cardiac arrest due to VT or VF OR spontaneous sustained VT causing hemodynamic compromise or syncope 

100

First line therapy for long QT syndrome

What are beta blockers? 

100

_______ is Characterized by transient or persistent coved type ST elevations in at least one right precordial EKG lead and associated with syncope and sudden death due to ventricular arrythmias.   ICD is recommended for patients with cardiac arrest or syncope due to arrythmia with classic pattern.  

brugada syndrome

Type 1: Coved ST segment elevation > 2mm in > 1 of V1-V3 followed by negative twave (only EKG that is

TYpe 2: Type 2: > 2 mm of saddleback shaped ST elevation 


Type 3: Type 1 or Type 2 pattern but less than 2 mm 

* Type 2 or 3 are nondiagnostic on their own and require further testing 

100

PR prolongation can result from conduction delay in the AV node.  In an EP Study, this interval is called the _____ interval

A-H interval

100

When heart block is transient or pending pacer placement, atropine or isoproterenol can be used in the short term.  Isoproterenol should not be used in this clinical scenario: 

acute myocardial infarction 


200

This therapy is recommended if there is a dominant PVC morphology that can be targeted and antiarrythmic therapy is ineffective

catheter ablation

200

Therapy is rarely necessary in AIVR but may be needed if loss of AV synchrony and acceleration of heart rate produces symptoms or a fall in blood pressure.  Options for intervention include: _____ or _____

accelerating the atrial rate through atropine or atrial pacing 

200

During VT catheter ablation the tissue containing the VT substrate is recognized as a region of

____ without needing to induce VT.

Low voltage and abnormal electrograms

200

In patients with cardiac sarcoid VT is the presenting complaint in 1/3 of patients.  An ICD is a class I indication for patients with sarcoid in the setting of _______ 

sustained VT or survivors of SCA or LVEF 35% or less if meaningful survival > 1 year.  

- granulomas heal leaving areas of fibrosis that can be substrate for scar-related reentrant sustained monomorphic VT 

- Immunosuppressant therapy may prevent/slow active disease progression and improve AV blocks, but is unlikely to resolve VT once fibrosis has formed

200

What treatment is recommended for patients with asymptomatic short QT syndrome? 

Nothing, observation alone. 

200

mutation found in 25-30% of patients with Brugada syndrome

SCN5A

200

Conduction delay in the His-Purkinje system causes prolongation in the _____ interval (think EP study)

HV interval 

200

Both sinus bradyarrythmias and AV block can be caused by this phenomenon without any underlying conduction system disease.

Autonomic/neurally mediated bradycardia 

increases in parasympathetic (vagal) tone can be triggered by a variety of events (hypersensitive carotid sinus syndrome, cough, syncope) 

300

This disorder describes patients who requires arrythmia suppression for symptoms or declining ventricular function suspected to be due to frequent PVCS (generally > ___ % of beats and predominately of 1 morphology) 

What is PVC cardiomyopathy?  What is 15%?


300

This ventricular tachycardia can resemble SVT with aberrancy and it is well treated with ablation

Bundle branch reentry VT 

300

VT catheter ablation mortality is of about _____% in patients with significant ventricular dysfunction. 

1-3 %

300

Name two class III indications for management of Hypertrophic Cardiomyopathy

EPS in patients with HCM or ICD implantation in patient with HCM genotype without risk factors for SCD

300

Prior to the development of Torsade de Pointes, the QTc interval is typically greater than ____ sec?

0.48 sec (480 ms)
300

Catecholaminergic polymorphic ventricular tachycardia is caused by a mutation in the cardaic ryanodine receptor and can cause bidirectional VT - triggered by stress or exertion.  In this condition, ICD's should be ____, and ____ given as treatment.  

avoided if possible. shocks from device can cause sympatheic activation and VT storms

Beta blockers (first line) + flecanide, left ventricular symptathetic denervation 

300

If the QRS complex on the EKG is norma in contour and duration, the AV delay almost always resides in the 

AV node 

300

This is the treatment for symptomatic prolonged autonomic/neurally mediated bradycardia when the block is likely to be evanescent but still requires treatment or until adequate pacing therapy can be established _____ (*anticholinergic - inhibit the muscarinic receptors) 

Atropine (1mg bolus, repeat every 3-5 min maximum of 3 mg) 

400

A 45 year old woman has a PVC burden of 15%. Her EF is 60% and she is asymptomatic.  Treatment of her PVCs with medications or ablation will improve her clinical outcomes.  TRUE OR FALSE

FALSE.  In the absence of evidence that PVCS are depressing ventricular function, suppression of PVCS with antiarrythmic medications has not generally been shown to improve outcomes.  

- These patients require frequent follow-up

- Many of their PVCs will spontaneously resolve

400

Name four features that help distinguish VT from SVT with aberrancy

AV dissociation 

precordial lead concordance (when all precordial leads on an electrocardiogram are either positive (positive concordance) or negative (negative concordance

AVR with monophasic R wave or notched Q wave 

atypical LBBB or RBBB

capture beats/fushion beats

400

In NICM percutaneous pericardial approach is often necessary to perform catheter ablation

because the location of the VT substrate is _________

Epicardial and intramural

400

ICD is reasonable (class IIa) in patients with the following conditions: 

spontaneous NSVT or abnormal blood pressure response to exercise who have additional SCD risk modifiers or high risk features 

400

What are the ion channels that are affected in LQTS types 1, 2, and 3?


Answer: Type 1 and type 2 are potassium channels, and type 3 are sodium channels (SCN5A)

400

In patients with Brugada syndrome who have recurrent ICD shocks or recurrent VT who have declined ICD, _____ or ______ are recommended therapies.

Quinidine or catheter ablation 
400

Conduction disturbance of the type 1 second degree AV block [improves/worsens] with exercise 

improves 

400

A gradually diminishing intensity of S1, widening of the a to c interval, terminated by a pause and an a wave not followed by a v wave can been on physical exam in this AV block

Type I second degree AV block 

500

Stroke volumes of PVCs are often insufficient to produce a palpable pulse, though PVCs are frequently audible.  On pulse oximetry, frequent PVCs can cause _____

bradycardia 

500

This is the preferred pharmacological agent to terminate sustained monomorphic ventricular tachycardia in hemodynamically stable patients

procainamide (contraindicated in ESRD due to risk of accumulation of its metabolities which can lead to QT prolongation and polymorphic VT) 


PROCAMIO Study 

500

The most common ECG abnormality in individuals with ARVC is __________

Twave inversions in V1-V3 or beyond

500

The two most common location of idiopathic ventricular tachycardia (VT in patients without structural heart disease) are ______ and _______.  BONUS: other locations include ______, ______, ______> 

Most common: right and left ventricular outflow regions 

Other areas:

-  papillary muscle arrythmias: EX. LV papillary muscle -> RBBB with S wave V4-V6 (posteromedial papillary muscle) or inferior rightward axis (anterolateral papillary muscle origin) 

- Annular arrhythmias (mitral or tricuspid) 

- Left fascicular reentrant tachycardia 

500

What is the class I indication for all patients who have a causative mutation identified for long and short QT syndromes?

Genetic testing

500

_____ characterized by J point elevation > 1 mm in at least 2 continguous inferior or lateral leads of the 12 lead EKG and a QRS duration < 120 ms in leads without J wave. It is particularly common among athletes, young men and african americans.  

Early repolorization syndrome 

classic EKG + VF or VT or syncope related to VT

 TX: ICD

500

Vagal maneuvers improve conduction disturbance in type ____ second degree AV block

Type 2 

500

This rhythm abnormality is shown in the intracardiac electrocardiogram 

No P wave (A) is followed by a His bundle potential, whereas each ventricular depolarization is proceeded by a HIS bundle potential.  

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