Anatomy
Transduction
Rotation & Inertia
#Facts
100

The base of the hair cells is bathed in ____________ (high concentration of Na+ and similar to CSF)


Perilymph



The apex of the hair cells is bathed in endolymph fluid (high concentration of K+)


100

The longest stereocilia, they can bend towards or away from this

Kinocilium

100

In the ampulla, the movement of the this fluid due to angular rotation deflects the stereocilia


endolymph


100

The structures that make up the labyrinth

3 Semicircular canals

2 otolith organs

200

The swelling (bulbs) at each end of the semicircular canals that sense rotational acceleration


Ampulla

200

Crista's ampullaris is surrounded by this membrane

Cupula



The stereocilia extend out from the crista into the gelatinous bulb called the cupula which is as tall as the ampulla


200

Which canal?

“Pitch”

Example: the nodding gesture, moving your head up and down


Superior (anterior) Canal


200

This type of acceleration is when force is applied to an object that moves in a line, like stopping in a car or falling down


Linear

300

These sense linear acceleration & position relative to gravity

Saccule & Utricle

300

Hair cells in the vestibular system __________ when their stereocilia are deflected towards to the kinocilium.

Depolarize

300

Which canal?

“Yaw”

Example: the gesture of shaking your head left to right


Horizontal Canal

300

The macula of the utricle and the macula of the sacculus is surrounded by this membrane

Otolithic Membrane

400

To help detect changes in linear acceleration, the fluid in your vestibular system has “ear stones” called this which experience inertia (like your body does in the car).


Otoconia

400

A backwards head tilt, equivalent to forward acceleration causes ___________

Depolarization


In this situation backwards head tilt and forward acceleration leads to hair cells sending the same signal!


400

Which canal?

 “Roll”

Example: the gesture of tilting your head left to right


Posterior Canal

400

The axons of the vestibulocochlear nerve project to this region, which are found in the brainstem ear the junction between the pons and medulla

Vestibular nuclei

500


The hair cells are embedded in the ampulla’s sensory epithelium called this.


Crista

500

Hair cells in the ____________ are all orientated in the same direction, while hair cells in the saccule and utricle have opposing orientations



ampullae

500

When we turn our head to the right, vestibular fibers innervating hair cells in which (L or R) horizontal canal will show increased firing?


Right



Key Point: Depolarization occurs on the side being turned to


500

This medication works to inhibit input into the vestibular nuclei and “vomiting center”


Anticholinergics like Scopolamine can be used as a prophylactic to motion sickness


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