Family ties
This virus family includes both the Ebola and Marburg viruses.
What is Filoviridae?
This West African country is the namesake of a rodent-borne arenavirus that causes hemorrhagic fever.
What is Lassa (Nigeria)?
This viral hemorrhagic fever may present with facial swelling, hearing loss, and pleural effusions in addition to bleeding.
What is Lassa fever?
The first-line treatment for Lassa fever is this antiviral, ideally given within 6 days of symptom onset.
What is ribavirin?
The 2014–2016 Ebola epidemic primarily affected Guinea, Liberia, and this West African country.
Sierra Leone
This family of rodent-borne viruses includes Lassa fever and South American hemorrhagic fevers.
What is Arenaviridae
The natural reservoir for Ebola virus is believed to be this type of animal.
What are fruit bats?
Rift Valley fever most commonly affects these two populations.
What are livestock and humans?
Name the FDA-approved vaccine used to prevent Ebola virus disease in high-risk settings.
What is rVSV-ZEBOV (Ervebo)?
This hemorrhagic virus was first identified in 1967 in Germany and Yugoslavia after laboratory workers were exposed to infected monkeys.
What is Marburg virus?
This family includes Rift Valley fever virus and other mosquito-borne bunyaviruses
What is Bunyaviridae (or Phenuiviridae)
Junín virus, which causes Argentine hemorrhagic fever, is transmitted by this rodent.
What is the drylands vesper mouse?
Conjunctival injection, hiccups, and hemorrhage are features of this African VHF with a high case fatality rate.
What is Ebola virus disease?
This diagnostic method, often used during outbreaks, detects viral RNA in blood or tissue samples.
What is RT-PCR (reverse transcription polymerase chain reaction)?
The 1976 Ebola outbreak was named after a river in this country.
What is the Democratic Republic of Congo (formerly Zaire)?
This hemorrhagic fever virus is transmitted by Hyalomma ticks and belongs to the Nairoviridae famil
What is Crimean-Congo hemorrhagic fever virus?
Crimean-Congo hemorrhagic fever is transmitted to humans primarily through this route.
What is tick bite or contact with infected animal blood/tissue?
This South American VHF has an effective live attenuated vaccine called Candid #1.
What is Argentine hemorrhagic fever (Junín virus)?
The management of most viral hemorrhagic fevers relies primarily on this type of supportive care.
What is fluid resuscitation and hemodynamic support?
This less-known arenavirus was responsible for a small outbreak among healthcare workers in South Africa in 2008.
What is Lujo virus?
Name the two viral families responsible for causing hemorrhagic fever with renal syndrome (HFRS) and hantavirus pulmonary syndrome (HPS), respectively.
What are Hantaviridae (or Bunyaviridae) and Hantaviridae?
This hantavirus, recently identified in northern Europe, has caused a surge in “vole fever” cases.
What is Puumala virus?
This viral hemorrhagic fever is associated with pulmonary edema, hypotension, and can progress to shock, often requiring ECMO.
What is Hantavirus Pulmonary Syndrome?
The main biosafety level required to work with live Ebola or Marburg virus in the lab.
What is BSL-4?
This South American arenavirus was discovered after a mysterious hemorrhagic fever outbreak in Bolivia in 1962.
What is Machupo virus?