Viruses
Retrovirus
Diplomatic Something or Other
Cell Block T
100

This structural feature, present in many enveloped viruses, is acquired from host membranes and contains viral glycoproteins essential for attachment and entry.

What is the viral envelope?

100

Retroviruses reverse the normal direction of genetic information flow by creating DNA from this template.

What is RNA?

100

This system allows organisms to defend themselves from pathogens while distinguishing self from nonself.

What is the immune system?

100

This is the first line of defense in the immune system, including physical and cellular components.

What is innate immunity?

200

This step in the viral life cycle involves the release of the viral genome from its capsid, often triggered by endosomal acidification or receptor‑induced conformational changes.

What is uncoating?

200

This virally encoded enzyme allows retroviruses to synthesize DNA from RNA.

What is reverse transcriptase?

200

These white blood cells arise from stem cells in the bone marrow and can travel through the lymphatic system.

What are leukocytes?

200

 These cells are first to encounter pathogens and later present antigens to helper T cells.

What are dendritic cells?

300

This common virus is annoying rather than deadly and causes the common cold.

What is the rhinovirus?

300

These flanking sequences in retroviral genomes assist in integrating viral DNA into the host DNA.

What are long terminal repeats

300

An improper functioning of the immune system can lead to the body attacking its own tissues, producing this category of diseases.

What are autoimmune diseases?

300

These innate immune cells digest cellular debris and pathogens.

What are macrophages?

400

This term refers to the complete virus particle consisting of nucleic acid and its protein coat.

What is a virion?

400

This major human disease is caused by a retrovirus and has driven decades of global research.

What is AIDS?

400

Vaccines work by exposing the body to a weakened or killed pathogen so the immune system can retain this.

What is immunological memory?

400

These lymphocytes kill infected or cancerous cells and work with dendritic cells to decide whether to activate acquired immunity.

What are natural killer (NK) cells?

500

 These structures allow viruses to attach to host cells and are found on the outer surface of many viruses.

What are protein spikes?

500

Retroviral genomes universally contain genes encoding coat proteins, reverse transcriptase, and these membrane-associated proteins.

What are envelope proteins?

500

 Food allergies may provoke this type of severe immune reaction that can be life‑threatening.

What is anaphylaxis?
(or “What are severe allergic reactions?”)

500

Dendritic cells travel to this organ after endocytosing invaders, where they present antigens to helper T cells.

What is the spleen?

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