General Info
What is the active ingredient in Vyvgart?
efgartigimod alfa-fcab
Can my primary care doctor prescribe Vyvgart?
Vyvgart can be prescribed by a neurologist or a neuromuscular specialist, as well as other healthcare providers who manage patients with generalized myasthenia gravis who are anti-acetycholine receptor antibody positive.
What causes gMG?
The reasons some people get it aren't fully understood. Generalized myasthenia gravis is an autoimmune disease. It is caused by the immune system mistakenly targeting healthy cells in the body.
I don't have insurance, can I still be treated with Vyvgart?
If you do not have insurance, you may be eligible to receive VYVGART through the My VYVGART Path Patient Assistance Program. After you and your neurologist decide on VYVGART, your doctor’s office will be able to enroll you in My VYVGART Path.
How well does Vyvgart work?
When added to their current generalized myasthenia gravis treatment, VYVGART helped global clinical trial participants with anti-acetylcholine receptor antibody positive generalized myasthenia gravis achieve: • Improved daily abilities: 68% (44 of 65) of participants on VYVGART achieved significant improvement in their ability to perform daily activities • Reduced muscle weakness: 63% (41 of 65) of participants on VYVGART achieved a significant reduction in muscle weakness
What are the most common side effects of Vyvgart?
Respiratory tract infection, headache, and urinary track infection
Is there a generic of Vyvgart?
There is no generic of Vyvgart.
Who diagnoses gMG?
Speak to a neurologist about your symptoms. A neurologist can confirm a diagnosis in anti-acetylcholine receptor antibody positive generalized myasthenia gravis.
My insurance denied my Vyvgart prescription, can you help me?
Let me gather some information. Do you have a prescription for VYVGART? [If yes] If your doctor’s office enrolled you in My VYVGART Path, the My VYVGART Path team can offer assistance to your provider with the appeal process. I can transfer you now if you like.
Is Vyvgart a pill?
Vyvgart injection is a preservative free, sterile, colorless to slightly yellow, clear to slightly opalescent solution supplied as 400mg/20mL (20 mg/mL) in one single-dose vial per carton.
How does Vyvgart work?
Works to reduce the IgG antibodies, including gMG-causing, harmful AChR antibodies.
What are immunoglobulins?
An immunoglobulin, also known as an antibody, is a Y-shaped protein made by the immune system. Antibodies attach to different things to let the immune system know that there is a potential threat that it will need to destroy or neutralize. Antibodies can attach to disease-causing substances like bacteria and viruses. The immune system makes 5 different types of antibodies (immunoglobulin G, IgA, IgE, IgD, IgM), each with a distinct role in protecting the body.
Can gMG be cured?
Can I enroll myself in My Vyvgart Path?
That is a good question. May I ask, do you have a prescription for VYVGART? [If yes] I can transfer you to My VYVGART Path to talk about the process of enrolling.
How should I store Vyvgart?
: VYVGART vials are refrigerated at 2°C to 8°C (36°F to 46°F) in the original carton to protect from light until time of use. Do not freeze. Do not shake.
Can someone under age 18 take Vyvgart?
No, Vyvgart is indicate for adults age 18 years of age and older. (FAQ 12- can be used to answer this)
What are biologics?
Biologics treat disease by using substances made from living organisms. These substances may naturally occur in the body or may be artificially created. A biologic must be approved by the Food and Drug Administration (FDA) to be used as a treatment in the United States
What are the symptoms of gMG?
: Serious muscle weakness is the main symptom of generalized myasthenia gravis. This muscle weakness often shows up in the face, with drooping eyelids being an early sign. Double or blurred vision, caused by weakness in the eye muscles, is another common symptom. Muscle weakness can extend to arms and legs. Smiling, chewing, swallowing, and breathing can also be affected. If you like I can text you link to gMG information.
Will my Medicare cover Vyvgart?
Medicare covers the majority of FDA-approved Part B drugs which would include VYVGART, but restrictions may apply in some cases. After you and your neurologist decide on VYVGART, your doctor’s office will be able to enroll you in My VYVGART Path. My VYVGART Path will work closely with your healthcare provider and insurance plan to determine your specific coverage for VYVGART.
I had a thymectomy. Can I still take Vyvgart?
Some patients in the VYVGART global clinical trial had a previous thymectomy. Talk to your doctor if you recently had a thymectomy or are planning to have one before considering treatment with VYVGART.
When was Vyvgart approved in the United States?
Vyvgart was approved by the FDA on 12/17/2021.
Is there a clinical trial that I can get involved in?
To be involved with an argenx clinical trial, it is best to talk to your neurologist. You can also look at the website clinicaltrials.gov to see if there is a trial near you.
I think I have gMG, what should I do?
: Speak to a neurologist about your symptoms. A neurologist can confirm a diagnosis in anti-acetylcholine receptor antibody positive generalized myasthenia gravis.
What's the limit on the co-pay card?
If you have anti-acetylcholine receptor antibody positive generalized myasthenia gravis, a valid prescription for VYVGART, and are commercially insured, you may pay as little as $0 dollars for VYVGART and receive up to $25,000 of assistance per calendar year. To learn more about the program and see the full terms and conditions, you can go to VYVGART.com.
Why is Vyvgart called a fragment? What does that mean?
VYVGART is a portion, or fragment of an antibody. This antibody fragment helps reduce the amount of IgG antibodies circulating the body, including the harmful acetylcholine receptor antibodies that cause anti-AChR antibody positive generalized myasthenia gravis symptoms.