WBC Basics
This is the normal total leukocyte count per µL of blood.
What is 4,000-10,000 per micro-liter?
This term describes a deficiency of WBCs.
What is leukopenia?
This type of leukemia involves blast-type cells and primarily affects children.
What is acute lymphoblastic leukemia (ALL)?
85% of NHL orginate from this type of cell.
What are B-cells?
This key retinal finding seen in leukemic patients appears as a red ring of blood surrounding a white center.
What are Roth spots?
This is the LEAST common WBC in circulation.
What are basophils?
This type of reactive leukocytosis is associated with bacterial infections.
What is neutrophilic leukocytosis?
This type of leukemia is only able to be diagnosed when the presence of Auer Rods is confirmed.
What is acute myelogenous leukemia (AML)
In Ann Arbor staging, involvement of lymph nodes on both sides of the diaphragm describes this stage.
What is stage III?
This B-cell malignancy is characterized by abnormal proliferation of plasma cells producing an M protein.
What is multiple myeloma?
What are neutrophils?
This type of reactive leukocytosis is associated with allergies, asthma, and parasitic infections.
What is eosinophilic leukocytosis?
This type of leukemia shows the presence of Philadelphia chromosome in 90% of cases.
What is chronic myelogenous leukemia (CML)?
The presence of ____ is CRUCIAL to diagnose Hodgkin's lymphoma.
What are Reed-Sternberg cells?
This NHL B-cell neoplasia produces abnormal plasma cells and monoclonal IgM.
What is Waldenström macroglobulinemia?
These are the two major progenitor cell lines arising from the hematopoietic stem cell.
What is myeloid and lymphoid progenitors?
This is the term used to describe a premature release of WBCs into the bloodstream.
What is a leukemoid reaction?
"shift to the left"
This type of chronic leukemia is of B-cell origin and may show fine, cytoplasmic projections (+100 points if you can name the treatment).
What are purine analogues?
This type of NHL is caused by EBV and the most common affected site is the jaw.
What is African Burkitt's lymphoma?
More than ___% of plasma cells present in the bone marrow supports the diagnosis of multiple myeloma.
What is 15%?
This progenitor gives rise to neutrophils, eosinophils, basophils, monocytes, platelets, and RBCs.
What are myeloid progenitor cells?
This disorder is caused by EBV, spreads through saliva, and produces fever, sore throat, lymphadenopathy, and splenomegaly?
What is infectious mononucleosis?
This type of leukemia is typically of B-cell origin and often includes a long asymptomatic period.
What is chronic leukocytic leukemia (CLL)?
Name one bacterial infection that can cause NHL (+100 if you can name the two on the slides).
What is:
H. PyloriThis syndrome is associated with Waldenström macroglobulinemia and can cause neurologic dysfunction, bleeding, hypervolemia, and retinal hemorrhages.
What is hyperviscosity syndrome?