Immunosuppression
What is the anti-inflammatory dose of steroids in felines? Immunosuppressive?
BONUS: Dogs AI? Dogs IS?
AI cats: 1-2 mg/kg/day
IS cats: 4-6 mg/kg/day
BONUS:
AI dogs: 0.5-1 mg/kg/day
IS dogs: 2-4 mg/kg/day
What is the anticoagulant:blood ratio of whole blood?
1:9
What 3 things are required for RBC synthesis from GI absorption?
iron, B12, folate
What medication is used in hospital to treat immune-mediated diseases before a patient is able to eat on its own?
IV dexamethasone
Rickettsiales are sensitive to what class of antibiotics?
tetracyclines (doxycycline)
What NSAID should NOT be given to cats? It can be given to dogs as an anti-clotting agent.
Aspirin
What blood product is indicated for coagulopathies, but not for hypoproteinemia?
What are signs of increased destruction anemia?
icterus, pigmenturia
What side effects should owners take their pet to the ER?
melena, lethargy, pale MM, not eating/drinking
What tick spreads Heartwater disease (E. ruminantium)?
Amblyomma marmoreum
This is a chemotherapy agent that stimulates the bone marrow to release platelets.
BONUS: What is it used to treat?
vincristine
BONUS: immune-mediated thrombocytopenia
Which blood group is the universal donor for dogs?
DEA 4
Petechia, ecchymosis, mucosal bleeds, and epistaxis are signs of what type of disorder?
primary hemostatic
What 5 tests are used to diagnose IMHA? How many need to be positive for IMHA to be diagnoses?
1. spherocytes
2. Coombs
3. autoagglutination
4. TBili elevation
5. flow cytometry
2/5 tests positive
This Anaplasma spp. results in limb edema, fever, and ataxia in equine.
Anaplasma phagocytophilum
Describe the lesion in the image. (On next slide of ppt)
severe, chronic, multifocal, granulomatous, splenitis
(severity, duration, distribution, exudate, tissue-itis)
A patient comes in who had gotten a blood transfusion 5 days prior. She has not been eating and appears icteric on presentation. What is occurring?
Delayed reaction --> extravascular hemolysis
If you perform a thoracocentesis and place it in a tube and it does not clot, what does this indicate?
hemorrhagic effusion
What is the biggest complication of IMHA?
thromboembolic disease
A dog presents in clinic after eating a dead fish found on the shore at the beach. What is the most likely disease?
Neorickettsia helminthoeca (Salmon-Poisoning Disease)
Name 2 side effects of long-term, high-dose steroids.
1. iatrogenic hyperadrenocorticism
2. muscle wasting
3. insulin resistance or diabetes (esp. in cats)
4. increased susceptibility to infection 5. GI ulcers
Describe a major crossmatch and a minor crossmatch.
Major Crossmatch: DONOR RBCs and PATIENT plasma/serum
Minor Crossmatch: DONOR plasma/serum and PATIENT RBCs
A 4 week old puppy presents for lethargy, yellow gums, and brown urine. What diagnostic tool should be used next?
BONUS: What is most likely cause?
abdominal radiographs
BONUS: ingestion of pennies
What is Evan's syndrome?
IMHA & IMTCP
This test is used for confirmation of Lyme disease.
Western blot