Epidermis
Dermis/Hypodermis
Accessory Structures
Skin Physiology
Immune System
100

Which layer of the epidermis consists of cells that are undergoing mitosis and eventually migrate to the stratum corneum layer to be sloughed off?

A. stratum basale

B. stratum granulosum

C. stratum lucidum

D. stratum spinosum 

a. stratum basale

100

The papillary and reticular layers of the dermis are composed mainly of ________.

  1. melanocytes
  2. keratinocytes
  3. connective tissue
  4. adipose tissue

c. connective tissue

100

Eccrine sweat glands ________.

  1. are present on hair
  2. are present in the skin throughout the body and produce watery sweat
  3. produce sebum
  4. act as a moisturizer

b. are present in the skin throughout the body and produce watery sweat

100

In humans, exposure of the skin to sunlight is required for ________.

  1. vitamin D synthesis
  2. arteriole constriction
  3. folate production
  4. thermoregulation

a. vitamin D synthesis

100

Which of the following cells is phagocytic?

  1. plasma cell
  2. macrophage
  3. B cell
  4. NK cell

b. macrophage

200

Which layer of your epidermis keeps you from drying out?

  1. stratum corneum
  2. stratum basale
  3. stratum spinosum
  4. stratum granulosum

a. stratum corneum 

200

The papillary layer of the dermis is most closely associated with which layer of the epidermis?

  1. stratum spinosum
  2. stratum corneum
  3. stratum granulosum
  4. stratum basale

d. stratum basale

200

Sebaceous glands ________.

  1. are a type of sweat gland
  2. are associated with hair follicles
  3. may function in response to touch
  4. release a watery solution of salt and metabolic waste

b.  are associated with hair follicles

200

What determines the color of skin?

The pigment melanin, produced by melanocytes, is primarily responsible for skin color. 

Melanin comes in different shades of brown and black. Individuals with darker skin have darker, more abundant melanin, whereas fair-skinned individuals have a lighter shade of skin and less melanin.

200

Which of the following cells is most important in the antibody/antigen (i.e. humoral) immune response?

  1. B cells
  2. T cells
  3. macrophages
  4. plasma cells

a. B cells 

300

Langerhans cells are commonly found in the ________.

  1. stratum spinosum
  2. stratum corneum
  3. stratum granulosum
  4. stratum basale

a. stratum spinosum

300

When we look at our fingers, we can see fingerprints. Which of the following layers of skin are we looking at in order to see the fingerprints?

A. papillary layer of the dermis

B. reticular layer of the dermis

C. hypodermis 

D. stratum corneum of the epidermis 


A. papillary layer of the dermis

300

Similar to the hair, nails grow continuously throughout our lives. Which of the following is furthest from the nail growth center?

  1. nail bed
  2. hyponychium
  3. nail root
  4. eponychium

b. hyponychium

300

In response to stimuli from the sympathetic nervous system, the arrector pili ________.

  1. are glands on the skin surface
  2. can lead to excessive sweating
  3. are responsible for goose bumps
  4. secrete sebum

c. are responsible for goose bumps

300

What is an example of natural immunity acquired passively?

- placental transfer of IgG antibodies from mother to fetus

- breastfeeding 

400

Which of the following cells are associated with the sensory function of skin?

A. Laangerhans cells

B. Kerationcytes

C. Melanocytes

D. Merkel cells

D. Merkel cells

400

Which of the following is not a function of the hypodermis?

  1. protects underlying organs
  2. helps maintain body temperature
  3. source of blood vessels in the epidermis
  4. a site to long-term energy storage

c. source of blood vessels in the epidermis

400

The hair matrix contains ________.

  1. the hair follicle
  2. the hair shaft
  3. the glassy membrane
  4. a layer of basal cells

d. a layer of basal cells

400

An individual has spent too much time sun bathing. Not only is his skin painful to touch, but small blisters have appeared in the affected area. This indicates that he has damaged which layers of his skin?

  1. epidermis only
  2. hypodermis only
  3. epidermis and hypodermis
  4. epidermis and dermis

d. epidermis and dermis

400

What is the reason that you have to be immunized with a new influenza vaccine each year?

  1. the vaccine is only protective for a year
  2. mutation
  3. macrophage oxidative metabolism
  4. memory response

b. mutation

500

Cells of the epidermis derive from stem cells of the stratum basale. Describe how the cells change as they become integrated into the different layers of the epidermis.

As the cells move from the stratum basale into the stratum spinosum, they begin the synthesis of keratin and extend cell processes, desmosomes, which link the cells. 

As the stratum basale continues to produce new cells, the keratinocytes of the stratum spinosum are pushed into the stratum granulosum. The cells become flatter, their cell membranes thicken, and they generate large amounts of the proteins keratin and keratohyalin. 

The nuclei and other cell organelles disintegrate as the cells die, leaving behind the keratin, keratohyalin, and cell membranes that form the stratum lucidum and the stratum corneum. The keratinocytes in these layers are mostly dead and flattened. Cells in the stratum corneum are periodically shed.

500

An individual using a sharp knife notices a small amount of blood where he just cut himself. Which of the following layers of skin did he have to cut into in order to bleed?

  1. stratum corneum
  2. stratum basale
  3. papillary dermis
  4. stratum granulosum

c. papillary dermis

500

Explain the differences between eccrine and apocrine sweat glands.

Eccrine sweat glands are all over the body, especially the forehead and palms of the hand. They release a watery sweat.

Apocrine glands are associated with hair follicles. They are larger than eccrine sweat glands and lie deeper in the dermis. They release a thicker sweat that is often decomposed by bacteria on the skin, resulting in an unpleasant odor.

500

Why do people sweat excessively when exercising outside on a hot day?

Sweating cools the body when it becomes warm. 

When the body temperature rises, such as when exercising on a hot day, the dermal blood vessels dilate, and the sweat glands begin to secrete more sweat. The evaporation of the sweat from the surface of the skin cools the body by dissipating heat.

500

Briefly describe the three different phases or lines of defense of the immune system. 

1. (Innate) Barrier System: the skin, its secretions, and the mucous membranes of the body.

2. (Innate) Phagocytic leukocytes, Fever/Inflammation


3. (Adaptive) Lymphocytes, Antibodies

- Antigen-specific responses

- Exposure results in immunologic memory 

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