Bioequivalence
Give a rough definition of what bioequivalence is
A drug that has less than 20% variance
Define respect for person
Exactly what it sounds like- respecting them and their autonomy, includes informed consent
What is a black box warning?
The most stringent drug warning from the FDA- these medications are very high risk and nurses must be very careful when administering
How many times a day would you administer a medication labeled "TID"
Three times a day
If a patient needs 75 mg of metoprolol and the medication comes in 25mg tablets. How many tablets should be administered
3 tablets
Why might someone not want to suddenly change generic drug manufacturers?
This may alter drug levels in systems, making either too high or too low amounts of drug in their system.
Define justice
Equal distribution of benefits and burden
What medications should be treated with the same caution as highly toxic/high alert medications?
Over-the-counter meds
What are some ways you could ensure that it is the right patient?
Asking them to state name/DOB, checking EMR/EHR, looking at picture in chart, checking arm band, etc.
An order is for 0.125 mg omeprazole and tablets come in .25 mg. How many tablets should be administered
0.5- cut the tablet in half is it can be (only scored pills, nothing that is enteric coated or slow release/dissolve)
Less than what percent variance is required for drugs to be considered bioequivalent?
20%
Define beneficence
The benefits outweigh the risk and that the patient/client is aware of both
What is a special step that must be taken when administering high alert medications
Must be confirmed and documented by 2 nurses prior
How many times total (at least) should the drug label be read?
Three times
An order for amoxicillin is placed for 750 mg, the medication comes in 250 mg/3 mL suspension. How many mL should be administered
9 mL
The same __ drug can have multiple __ names
The same generic drug can have multiple brand names
Define nonmalifecence
Avoiding actions that could result in injury, "do no harm"
When is the most likely time for an adverse event related to medications
When transitioning care settings (ex. hospital to home)
What are the steps to administering a phoned-in order?
The 6 rights, the nurse reads back the order to the prescriber, prescribed must sign order within 24 hours
An order for a medication is 1 g, tablets come in 250 mg in 4 mL suspension. How many mL should be administered
16 mL
Why might a brand create a bioequivalent drug
The patent for the brand name has run out
How many phases are required in drug trials
Four- groups of 20-80, 100-300, 1000+, continued studies on drug while it is already in market
What can a patient do to ensure the healthcare team is aware of all prescriptions being taken
Bring a list or even a bag with all medications the patient is taking to appointments
What are the "bonus' rights to drug administration?
Right assessment, right education, right of patient to refuse,
The prescriber orders 80 mEq BID and the medications comes in 20 mEq in 5mL suspension. How many mL total will the patient receive in a day?
40 mL