EASY
This term means prevention of blood loss.
Hemostasis
Is it possible for an “Rh negative” mother and an “Rh positive” father to have an “Rh negative” baby?
Yes
Enumerate the 4 mechanisms involved in hemostasis
Vascular constriction
Formation of a platelet plug
Formation of a blood clot
Growth of fibrous tissue into the blood clot
It is a disease of the fetus and newborn child characterized by agglutination and phagocytosis of the fetus’s RBCs?
Erythroblastosis fetalis
What is the factor that initiates the initiation of the extrinsic pathway?
Tissue factor
Protein c will inactivate what clotting factor/s?
Factor V and VIII
A condition that cause excessive bleeding that occurs almost exclusively in males.
Hemophilia
When a patient’s platelet count is 50, 000 uL, what will likely to occur?
A. The patient will die immediately
B. Overproduction of clot
C. The patient will bleed
D. Nothing will happen to the patient
A feedback mechanism that is involved in the formation of clot.
Positive Feedback
Test that measures the following, Platelet number and function, von Williebrand Factor and Vascular Integrity.
Bleeding time
The principle of blood typing is based on which of the following?
A. Agglutination reaction
B. Reaction with Lectins
C. Monoclonal antibody production
D. Rouleaux formation
A. Agglutination Reaction
The agglutinins are produced by_____________.
bone marrow and lymph gland cells
Test the measure the following Factors VIII,IX,X,XI,XII,II,V and Fibrinogen
-APPT or Activated Partial Thromboplastin Time
A plasma protein that is important in platelet adhesion.
von Willebrand factor (vWf)
Test that measures the following Factors II,V,VII,X and Fibrinogen
Prothrombin Time
This type of coagulants predominate in the bloodstream.
A. Anticoagulant
B. Procoagulant
C. Prothrombin
D. Fibrinogen
A. Anticoagulant
A vitamin that is required for the formation of prothrombin in the liver.
Vitamin K
Naruto’s forward and reverse BT results:
Anti-A(+), Anti-B(-), A cells(-), B cells(+), O cells(-)
Sasuke’s forward and reverse BT results:
Anti-A(-), Anti-B(-), A cells(+), B cells(+), O cells(-)
If Naruto will donate blood to Sasuke, what will be the result of cross matching?
ANSWER: Incompatible Major, Compatible Minor
Major = Patient Serum (antibody) + Donor Red Cell (antigen)
Minor = Patient Red cell (antigen) + Donor Serum (antibody)
Sasuke has antibodies for Naruto’s RBCs (antigen) seen in Major Crossmatch
Sasuke has not have antigens for Naruto’s antibodies seen in Minor crossmatch
A cofactor required to convert prothrombin to thrombin.
a. Mg
b. Mn
c. Na
d. Ca++
Test for vascular and platelet function?
Bleeding test
Type A blood contains type A agglutinogens and anti-B agglutinins, and type B blood contains type B agglutinogens and anti-A agglutinins. Type AB blood contains _____ agglutinogens and _____ agglutinins.
Contains both A and B agglutinogens
No agglutinins
Test for overall clotting availability
Clotting time, APTT, PT, THROMBIN TIME, FIBRINOGEN ASSAY
Sometimes, when recipient and donor bloods are mismatched, immediate hemolysis of RBCs occurs in the circulating blood due to the antibodies activating the complement system, which releases proteolytic enzymes that rupture the cell membranes. This complement system is called the_____________.
Lytic Complex
All of the following is true about Rh antigens, except:
a. Warm antibodies are produced against it.
b. It is not uncommon to see several Rh antibodies in a patient.
c. The nomenclature of Rh antigen is derived from the Rhogam antigen produced by rhesus monkey, thus initial “Rh” is a shorthand for “Rhogam”
d. All are not true
c. The nomenclature of Rh antigen is derived from the Rhogam antigen produced by rhesus monkey, thus initial “Rh” is a shorthand for “Rhogam”
The Bombay phenotype is a result of
a. “hh” genotype
b. Mutation of FUT1 gene
c. Inability to produce the enzyme alpha-fucosyltransferase
d. None of the above
e. All of the above
e. All of the above