Know the Language
Vital Signs Don’t Lie
Positive Screen… Now What?
End-Organ Injury = Sepsis
Treatment & Teamwork
100

Infection with abnormal vital signs but no end-organ injury

What is a serious infection?

100

The most commonly missed and underestimated vital sign in obstetric patients

What is respiratory rate?

100

The purpose of Step 2 after a positive serious infection screen

What is bedside sepsis evaluation?

100

A renal finding that meets end-organ injury criteria

What is creatinine doubling from baseline or ≥1.2 mg/dL?

100

The maximum time antibiotics should be delayed once sepsis is suspected

What is 1 hour?

200

Infection with end-organ injury related to a dysregulated host response

What is sepsis?

200

A single respiratory rate that independently triggers a serious infection screen

What is ≥24 breaths per minute?

200

Three core components assessed during bedside evaluation

What are patient concerns, alternative diagnoses, and infection source?

200

A hematologic marker of end-organ injury

What are platelets <100,000?

200

The recommended initial fluid bolus for septic shock

What is 30 mL/kg ideal body weight?

300

The reason CMQCC introduced the term “serious infection”

What is to identify high-risk patients before end-organ injury occurs?

300

Why heart rate must be sustained before meeting screening criteria

What is to avoid false positives from transient changes?

300

The default action if no alternative diagnosis is identified

What is to proceed to action and treat infection?


300

A respiratory finding that qualifies as end-organ injury

What is SpO₂ <92% or new oxygen requirement?


300

Initial fluid recommendation for serious infection without end-organ injury

What is 500–1,000 mL (up to 1–2 L based on response)?

400

A common cognitive bias where abnormal findings are gradually accepted as “normal”

What is normalization of deviance?

400

The required method for temperature measurement when screening for infection

What is an oral temperature?

400

How often vital signs should be reassessed after a positive screen

What is at least every 30 minutes?

400

A neurologic sign of end-organ injury

What is new confusion, agitation, or unresponsiveness?

400

The most important action after giving fluids and antibiotics

What is planned reassessment of vitals, perfusion, and clinical response?

500

According to CMQCC teaching points, this exact phrase should NOT appear in the chart unless end-organ injury is present.

What is “rule out sepsis”?

500

Why blood pressure is not used as a screening criterion for serious infection

What is because it is more useful as an indicator of septic shock, not early screening?

500

Why bedside evaluation is considered the most important step in the pathway

What is because it confirms infection, excludes other diagnoses, and identifies end-organ injury?

500

A postpartum patient with suspected infection has received fluids but now has SpO₂ 91% on room air, new confusion, and platelets of 95,000.

What is sepsis (infection with end-organ injury)?

500

For a patient with septic shock and an ideal body weight of 60 kg, CMQCC recommends this total crystalloid volume to be given within the first 3 hours.

What is 1.8 liters of crystalloid (30 mL/kg × 60 kg)?

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