Biomarkers
Type 1/2 SLE
Adherence
Precision
Pop Quiz
100

This kind of biomarker indicates that a specific kind of therapy is more likely to be effective.

What is a theranostic biomarker?

100

The two different patterns of type 2 SLE.

What are intermittent and persistent?

100

Hydroxychloroquine levels from this type of sample are more precise.

What is whole blood? 


Whole blood is more precise than serum, and can be 2-5x the plasma/serum concentration. Goal is 500 - 2000.

100

This system is responsible for clearing monoclonal antibody-based treatments from the body.

What is the lysosomal reticuloendothelial system (RES)?

100

This person is widely considered to be the best reality TV show host of all time, recently completing the 41st season of his wild show. 

Disclaimer: the creator of this jeopardy game strictly denies binge-streaming half of these seasons during the pandemic.

Who is Jeff Probst?

200

This kind of gene signature is increased in lupus patients with high serologic activity (anti-DNA and RNP antibodies).

What is the interferon gene signature?

200
After implementing the type 2 PGA, the Duke SLE clinic saw a documented improvement in this aspect of clinical care.

What is the rate of documented type 2 SLE management? (increased from 53% to 89%, p = 0.03)

200

Turning this feature on in an EPIC-based electronic health record can inform providers of pharmacy fill data.

What is an adherence report? (Surescripts report also acceptable).

200

An increase in this patient factor has been associated with decreased drug levels of TNF inhibitors, tocilizumab, and rituximab?

What is BMI? (CRP is also acceptable)

200

This person was the most recent Bachelorette, currently engaged to Nayte O.

Who is Michelle Young?

300

The approximate percentage of rheumatoid arthritis patients with a positive ANA before treatment.

What is 30? (anything between 24 and 50% is acceptable)

300

The approximate percentage of SLE patients with only active type 1 SLE symptoms and NO or MINIMAL type 2 symptoms).

What is 11%?

Active type 1, low type 2: 11% (type 1 SLE)

Active type 1, high type 2: 33% (Mixed SLE)

Inactive type 1, high type 2: 28% (type 2 SLE)

Inactive type 1, low type 2: 28% (inactive SLE)


300

When addressing medication adherence with patients, this conjunction is preferred over the word "but."

What is the word "and?"

Other tips: Avoid jargon, teach-back, empathize, align with patient's goals, invite questions.

300

This percentage of RA patients on adalimumab will eventually develop anti-drug antibodies if they are NOT treated with methotrexate?

What is 50% (anything over 40% is acceptable)

300

This co-star of High School Musical, The Musical, The Series broke up with Olivia Rodrigo, inspiring the creation of one of the greatest Pop albums of all time.

Who is Joshua Bassett?

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