Homographs
One of me is to guide or direct, the other is a heavy metal.
Lead
We are a group of three words. One of us is a passage in a store, another is a contraction for "I will," and the third is a small island. What are we?
aisle, I'll, and isle
I'm trying to have a more optical outlook on life.
Optimistic
Motel
motor and hotel
SEASON, SEASHORE, SEARCH, SEAHORSE
Search - the others contain the word "sea."
One of me means to plant seeds while the other means a female pig
Sow
We are a percussion instrument and a character that represents a concept. What are we?
cymbal and symbol
The dentist gave me a shot of amnesia so I wouldn't remember the pain.
Anesthesia
Electrocute
To injure or kill by an electric shock, blending electric and execute
APPLE, BANANA, GRAPE
Banana, all the others have an odd number of letters
One of me is the substance or meaning of something while the other is a state of peaceful happiness.
Content
One is a painter's board, another is a wooden platform for shipping, and the third is the roof of your mouth. What are we?
palette, pallet, and palate
The villain tried to seduce the hero's identity from him.
Deduce
Sitcom
A type of TV show that is a situation comedy
SHEEP, DEER, FISH, COW
Cow - the others are both singular and plural.
One of me is a substance burned for its fragrance while the other means to make someone very angry
Incense
I mean careful and cautious in your actions, and my partner means separate and distinct. What are we?
discreet and discrete
The public library is a great suppository of knowledge.
Repository
Pixel
The smallest element of a display screen, from picture and element
LISTEN, SILENT, ELATION, ENLIST
Elation: is not an anagrams of the others.
One of me is an agricultural tool while the other means to cause distress to someone.
Harrow
I am a sarcastic or taunting remark, while my partner means to be in agreement with something. What are we?
gibe and jibe
All the houses on our street are contagious.
Contiguous
Gerrymander
A practice of manipulating electoral districts. It's a combination of the name Gerry (a Massachusetts governor) and salamander, due to a bizarre district shape.
KNIGHT, HONEST, DEBT, SHIP
Ship - does not contain a silent letter