Sam
Sam's PhD student who he works with
Who is Connor?
Charles's postdoc that he works with
Who is Camila?
In 1947, Dr. Farber achieved the world's first successful remisssion of ALL in children by introducing this non-standard treatment
chemotherapy
Often utilized as a model antigen to track tetramer kinetics in syngeneic mouse models, this protein makes up about 60% of the total protein in egg whites.
What is ovalbumin?
Held every October, this massive three-day rowing event draws over 11,000 athletes to the Charles River, making it the world's largest race of its kind.
What is the Head of the Charles Regatta?
Sam's favorite room to do TC
What is the lenti room?
His sport in college
What is rowing?
The author of the Emperor of all Maladies
Who is Siddhartha Mukherjee?
Driven by chronic TCR stimulation, this high-mobility group (HMG)-box transcription factor is now recognized as the central epigenetic master regulator that permanently commits CD8+ T cells to an "exhausted" state.
What is TOX?
This Boston neighborhood, known for its shops, restaurants, and proximity to Boston University, is centered around the intersection of Beacon Street and Harvard Street.
What is coolidge corner
Sams favorite lunch
What is eggs and sweet potato?
Charles' Hometown
What is Needham, Massachusetts?
In 1948, a pediatric patient dubbed "Jimmy" spoke on national radio from his hospital bed to raise money for a TV so he could watch this Boston baseball team, launching a massive charity movement.
Who are the Boston Braves?
This inhibitory receptor, often highly expressed on exhausted T cells in the tumor microenvironment, binds to CD155 and is currently being targeted in clinical trials by agents like tiragolumab.
What is TIGIT?
Spanning the Charles River to connect Boston's West End to Charlestown, this bridge is famous for its distinctive concrete Y-shaped towers and cables.
What is the Zakim Bridge?
This Dutch university, founded in 1575, is Sam’s home university.
What is Leiden University
Charles' dog's name
Who is Truman?
Cancer's gross appearance resembled this animal leading to its name as cancer.
What is a crab?
This transcription factor is a driver of tissue-resident memory T cell differentiation, tissue retention, and cytotoxic function.
What is Hobit?
To get an Uber from downtown Boston directly to Logan Airport, your driver will likely take this tunnel, named after a famous Boston Red Sox left fielder.
What is the Ted Williams Tunnel?
Colors of Sam's hometown (you can use your phone)
What is the Green & Yellow?
Favorite Fast Food
What is Taco Bell?
The cancer that Drs. Emil Frei III and Norman Jaffe first used pre-operative chemotherapy to facilitate the world's first limb-salvage surgeries
What is osteosarcoma
These 15–31 amino acid peptides, extended beyond the minimal 8–14 amino acid CD8⁺ T-cell epitope, are used in neoantigen vaccines because they must first be taken up and processed by professional antigen-presenting cells, reducing direct MHC-I loading on non-specialized cells and promoting effective T-cell priming.
What are synthetic long peptides (SLPs)?
Just a short walk down Beals Street from the main intersection of Coolidge Corner, you'll find a National Historic Site marking the 1917 birthplace of this U.S. President.
Who is JFK?