What things are the brain's Reward System responsible for? How does that influence or affect addiction?
Brain's Reward System:
Feeling pleasure and enjoyment, Motivation and drive, Learning what to repeat, Reinforcing social connections
Because drugs can influence the reward system, they can also hijack the response making using the drug the most important thing.
What is addiction, and what makes it difficult for someone to stop using a substance?
When a drug or substance takes over control and you can't stop even if you want to.
The brain is basically rewired to demand the drug so it can be very difficult to overcome.
Some drugs have chemical structures that resemble the brain's natural neurotransmitters. What can happen when these drugs attach to receptors on neurons?
A. They always make neurons communicate normally.
B. They can activate receptors and disrupt normal brain messages.
C. They permanently stop all communication between neurons.
B. They can activate receptors and disrupt normal brain messages.
Someone starts using nicotine regularly. After a while, when they haven't had any, they feel irritated, restless, and really want it. They use nicotine again and feel better for a while. What cycle might be starting?
The Addiction Cycle
What are common symptoms of nicotine withdrawal? Name at least 2.
Common symptoms include:
Strong cravings
Irritability, anxiety, and restlessness
Difficulty concentrating
Sleep disturbances
Increased appetite
Low mood
What are some examples of things that you do that produce dopamine?
Sports, music, friends, eat good food, watch a good movie, play video games, time with pet, etc.
Can someone be addicted to a substance even if they no longer enjoy using it?
Yes! Someone may continue using to relieve cravings or withdrawal symptoms, or because substance use has become a strongly learned behavior.
Cocaine can interfere with the normal recycling of dopamine between neurons. What effect can this have?
A. Dopamine signaling becomes stronger or lasts longer than normal.
B. The brain immediately stops producing dopamine.
C. Dopamine can no longer affect the reward system.
A. Dopamine signaling becomes stronger or lasts longer than normal.
Taylor has been vaping for a while. Taylor takes a hit and soon thinks, βI want to do that again!β What is happening in the brainβs reward system?
A. Nicotine and THC increase dopamine, helping the brain learn to repeat the behavior.
B. Nicotine and THC turn off the reward system.
C. Nicotine and THC makes the brain stop producing dopamine.
D. Nothing changes in the reward system.
A. Nicotine and THC increase dopamine, helping the brain learn to repeat the behavior.
What signs suggest Tyler may have developed an addiction, and what should Tyler do to safely get help?
Signs of possible addiction:
Taking more medication than prescribed.
Continuing to use it for emotional relief rather than pain.
Experiencing cravings and difficulty stopping despite wanting to quit.
What Tyler should do:
Tell a healthcare provider or trusted adult.
Seek medical guidance for managing withdrawal and stopping safely.
Ask about treatment and support for opioid use disorder.
Name a neurotransmitter affected when using alcohol, nicotine or other drugs?
Dopamine.
How does dopamine contribute to addiction?
Dopamine contributes to cravings.
Who is at higher risk of developing addiction? And why?
Jake. Because his brain is not yet fully developed so the drug will hijack that developmental process.
What signs suggest that Chris may be developing an addiction to alcohol, and how might the brain's reward system be contributing?
Signs of addiction
Alcohol is becoming more important than other activities.
Chris has difficulty enjoying social situations without drinking.
Chris continues drinking despite negative consequences.
Chris wants to cut back but struggles to do so.
Key takeaway: Chris may be losing control over drinking as the brain increasingly learns to prioritize alcohol.
Scenario:
After drinking heavily every day for several months, 19-year-old Ryan decides to stop drinking alcohol completely.
Within hours, Ryan begins sweating, shaking, and feeling extremely anxious. Later, Ryan becomes confused, and the shaking gets worse.
A friend tells Ryan, "Just tough it out. Withdrawal is uncomfortable, but it can't hurt you."
Question:
Why could Ryan's withdrawal be dangerous, and what should Ryan do?
Alcohol withdrawal can be life-threatening. Ryan needs immediate medical evaluation.
How can this affect the messages being sent throughout the brain?
As a result, substances can change how we think, feel, behave, and make decisions.
Scenario:
After struggling with addiction, Jordan decides to stop using drugs. At first, cravings are strong, and everyday activities don't feel as enjoyable as they once did.
Jordan begins attending counseling, exercising, spending time with supportive friends, and practicing healthier ways to handle stress.
Over time, the cravings become more manageable, and Jordan begins enjoying life without drugs again.
Question:
How can Jordan's brain change during recovery, and why is practicing new habits important?
Neuroplasticity. The brain will wire the new behavior if she keeps practicing it.
The Addiction Cycle includes 4 stages.
1. Trigger. - Stress, emotions, or certain situations
2. Craving. - A strong urge to use the substance
3. ?
4. Temporary Relief - Uncomfortable feelings briefly decrease
Identify the missing stage
Substance use
What might be happening to Ethan, and why is it important for him to be honest with his healthcare team about his substance use?
Ethan may be experiencing alcohol withdrawal, which can become life-threatening.
Someone who has become physically dependent on a substance decides to stop using it. Withdrawal can be uncomfortable, but with certain substances, it can become life-threatening.
Which TWO substances are especially known for potentially life-threatening withdrawal, and why?
A. Nicotine and cannabis β because stopping them causes the brain to shut down.
B. Alcohol and benzodiazepines (such as Xanax or Valium) β because suddenly stopping can cause dangerous overactivity in the nervous system.
C. Opioids and nicotine β because withdrawal from either always causes seizures.
D. All substances have the same withdrawal risks.
B. Alcohol and benzodiazepines.
Both affect systems that help regulate nervous system activity.
With physical dependence, suddenly stopping can cause severe nervous system overactivity.
Complications can include seizures, delirium, and potentially death.
Medical supervision may be necessary for safe withdrawal.
How can Cameron's brain trigger a craving before any alcohol has been consumed?
The brain has created an association with her friend's house and drinking alcohol.
Why might one person develop an addiction while another person using the same substance does not?
Addiction risk is influenced by several factors, including:
Genetics and family history
Age when substance use begins
Stress, trauma, and mental health
Frequency and amount of substance use
Environment and social influences
What is happening in Morgan's brain and body that makes stopping so difficult, even though Morgan wants to quit?
Tolerance, physical dependence, withdrawal, and cravings.
Why is the belief that natural substances are automatically "safe" dangerous, and what should someone do in this situation?
Natural substances can still affect brain receptors, cause dependence, and interact dangerously with other drugs. Unconsciousness and abnormal breathing are medical emergencies. Call 911 immediately.
Scenario:
Some disposable vapes contain enough nicotine in their e-liquid to equal the nicotine content of hundreds of cigarettes. Certain vaping devices can also deliver nicotine very efficiently, making it possible to absorb large amounts in a short time.
During a party, Jordan repeatedly uses a high-nicotine vape. After a while, Jordan feels nauseated, dizzy, and shaky. Then Jordan starts vomiting, becomes confused, and has trouble standing.
A friend says, "Just sit down. It'll wear off."
Question:
What might be happening to Jordan, and which symptoms tell you that medical help is needed?
Jordan may be experiencing nicotine poisoning (nicotine toxicity).
Early warning signs: Nausea, dizziness, headache, sweating, shakiness, and a racing heartbeat.
Danger signs: Repeated vomiting, severe confusion, difficulty walking or standing, fainting, seizures, or difficulty breathing.
What to do: Stop nicotine exposure, tell a trusted adult, and seek immediate medical assistance for severe symptoms.