A Tale of Two Tempos
IBS-D correlates to a type 6 or 7 on this scale.
What is the Bristol Stool Form Scale?
This therapy for moderate-severe Crohn’s should not be used long‑term (maintinance) due to adverse effects.
What are corticosteroids.
Despite a short plasma half‑life of 1–2 hours, this drug class provides prolonged acid suppression due to irreversible enzyme inhibition.
What are PPIs (Proton Pump Inhibitors)
This is the more damaging toxin produced by some C.diff strains.
What is Toxin B?
This common OTC medication is one of the leading causes of DILI?
What is Acetaminophen?
This agent availible over the counter is 1st line pharmacological treatment for IBS-C.
What is Polyethylene Glycol (Miralax®)?
This biomarker is preferred by both AGA and ACG for noninvasive assessment of intestinal inflammation in IBD.
What is Fecal calprotectin
P-CABs (Potassium Competitive Acid blockers) have a (faster/slower) onset of action compared to PPI's?
Faster.
C.diff spores are highly transmissible via the ____ route.
What is Fecal-Oral
DILI is often categorized as hepatocellular, mixed or _______?
What is Cholestatic?
This minimally absorbed antibiotic is recommended to treat global IBS‑D symptoms.
What is rifaximin (Xifaxan®)?
This biologic class for moderate-severe IBD, includes infliximab and adalimumab.
What are Anti‑TNF agents?
This drug has a CYP2C19 drug metabolism interaction with Clopidogrel (Plavix®)
What is Omeprazole.
Symptoms, A positive PCR test and this are required for an active C.diff Infection?
What is a positive Toxin result?
What is the treatment for intrinsic DILI secondary to acetaminophen toxicity?
N-acetyl-cysteine (NAC)
This mixed opioid receptor modulator is conditionally recommended by both AGA and ACG for IBS‑D.
What is eluxadoline?
This nutritional deficiency is common in Crohn’s involving the terminal ileum.
What is Vitamin B12 deficiency?
P-CABs (Potassium Competitive Acid blockers) are reccomended for use in ______.
What is H.Pylori erradicaiton.
This discontinued agent used as adjunctive treatment to c.diff infections is now discontinued.
What is Bezlotoxumab?
These physicians created the nomogram utilized in Acetaminophen overdoses.
Who is Rumack and Matthew
These TCAs contain a secondary amine group, distinguishing them from their counterparts.
What are Desipramine and Nortriptyline?
This biologic class includes vedolizumab and targets gut‑specific lymphocyte trafficking.
What is Anti‑integrin?
Approved in the U.S. in 2022, this PCAB is the first in its class to reach the U.S. market.
What is vonoprazan (Voquezna®)
This antibiotic class is associated with hypervirulant strains of C.diff
What are the fluoroquinolones?
L-Carnitine can be utilized to restore mitochondrial function in this drug induced liver injury.