Cell Cycle Basics
Mitosis
Chromosomes and DNA
Cell Cycle Control and Signals
Cancer and Cell Cycle Errors
100

This stage of the cell cycle is where the cell performs its usual functions and may enter G₀ if it chooses not to divide.  

What is G₁?

100

In this phase, chromosomes condense and the nuclear envelope breaks down.  

What is prophase?

100

DNA winds around these proteins to form nucleosomes.  

What are histones?

100

This term describes a molecule that stimulates or inhibits a cellular event.  

What is a signal?

100

Cancer is described as a disease in which this process occurs repeatedly without end.  

What is cellular reproduction?

200

During this phase of interphase, DNA replication occurs, producing sister chromatids.

What is the S phase?

200

Chromosomes line up along the equatorial plate during this phase.  

What is metaphase?

200

Humans have this number of chromosomes.  

What is 46?

200

These internal regulatory proteins must be destroyed at the correct time for the cell cycle to progress normally.  

What are cyclins?

200

Mutated proto-oncogenes become these cancer-causing genes.  

What are oncogenes?

300

This checkpoint ensures DNA has replicated correctly before mitosis begins.  

What is the G₂ checkpoint?

300

Sister chromatids separate and move toward opposite poles in this phase.

What is anaphase?

300

This term describes the thin, threadlike appearance of DNA and proteins before condensation.  

What is chromatin?

300

Cells stop dividing when they touch due to this phenomenon.  

What is contact inhibition?

300

These genes normally inhibit the cell cycle and promote apoptosis.  

What are tumor suppressor genes?

400

This stage of the cell cycle includes mitosis and cytokinesis.  

What is the M phase?

400

This structure made of microtubules helps pull chromatids apart.  

What is the spindle?

400

Duplicated chromosomes consist of two identical DNA strands known as these.  

What are sister chromatids?

400

This external signal stimulates skin cells near an injury to divide.  

What is epidermal growth factor (EGF)?

400

Cancer cells can spread to new locations through this process.  

What is metastasis?

500

This term describes the orderly sequence of stages between the formation of a new cell and its division into two daughter cells.  

What is the cell cycle?

500

Plant cells form this structure during cytokinesis instead of a cleavage furrow.  

What is the cell plate?

500

This region holds sister chromatids together until anaphase.  

What is the centromere?

500

These repeating DNA sequences at chromosome ends shorten with each division.  

What are telomeres?

500

This chromosomal event, such as the formation of the Philadelphia chromosome, can contribute to cancer development.  

What is a translocation?