Psychotic Disorders
Which of these would be for management of psychosis?
A. Haldol
B. Prozac
C. Zoloft
D. Lexapro
A. Haldol
A. Haldol
B. Clozapine
C. Seroquel
D. Geodon
Clozapine
The neurogenic theory of depression tells us that:
Existing neurons are able to repair themselves
Brain can make new neurons
Hippocampal volume has shrunk
The action of anxiety drugs are similar to the action of with substance of abuse?
Alcohol
What is the mechanism of action for mood stabilizers?
Theorize it may have some neurogenic properties and may block sodium/calcium channels but they aren't really sure
Most antipsychotics work to regulate which 2 primary neurotransmitters?
Dopamine and Serotonin
Which antipsychotic is neutral for weight gain risk?
A. Risperdal
B. Clozaril
C. Abilify
D. Geodon
C. Abilify
Blocking histamine receptors would cause side effects of
Do benzos raise, lower, or have no effect on the seizure threshold?
Raise
Which medication is the gold standard for treatment of Bipolar Disorder?
Lithium
Antipsychotics exhibit their side effects in which pathways?
A. Mesolimbic
B. Mesocortical
C. Nigrostriatal
D. Tuberoinfundibular
C/D
A. Risperdal
B. Haldol
C. Prolixin
D. Seroquel
A. Risperdal
Tricyclic antidepressants primarily block which neurotransmitters? Pick all that apply
Serotonin
Dopamine
NE
GABA
By what percentage do the doses of benzos need to be cut for the elderly?
50
Salt intake must increase/decrease/remain the same when on Lithium.
remain the same
How many generations of antipsychotics are there and what is the primary difference as it relates to neurotransmitter effects?
Two - Generation 1 is more potent D2 than 5ht and Generation 2 is reverse
Which antipsychotic has the serious side effect of agranulocytosis?
Clozaril
Wellbutrin Primarily blocks which neurotransmitter?
A. Dopamine
B. Serotonin
C. GABA
D. NE
A. Dopamine
Benzos are agonists for which NT?
GABA
Which mood stabilizer results in a serious side effect of Steven Johnson Syndrome?
Lamictal
Tegretol
Depakote
Trileptal
Lamictal
Extrapyramidal side effects are a bigger concern with which generation?
Generation 1
What makes Abilify unique related to other antipsychotics?
It is partial agonist at D2.
Which class of antidepressants requires adherance to a strict diet?
MAOI
The FDA recommends that benzos only be used for what period of time?
2-4 weeks
Which anticonvulsant has the added benefit of weight loss?
Lamictal
Topamax
Trileptal
Neurontin
Topamax