CKD
phritic, phrotic
Crystal gems
In your genes
Miscellaneous
100

GFR 60-89 ml/min/1.73m2 is categorized as...

Stage G2

100
Hallmark features of the nephrotic syndrome include a urine protein excretion of > ________, as well as hypoalbuminemia, hypercholesterolemia, and edema.

3500mg/24h


or a urine protein-creatinine ratio >3500mg/g

100


Calcium oxalate


Envelope; dumbbell; needle

Associated with hypercalciuria, hyperoxaluria, ethylene glycol poisoning.

100

This most common inherited kidney disorder can involve intracranial cerebral aneurysm, MVP, hepatic cysts, and diverticulosis

Autosomal dominant polycystic kidney disease

100
With ambulatory blood pressure monitoring, normal BP includes a 24-hour average BP of...

<115/75mmHg


(daytime average <120/80; nighttime average <100/65)

200

CKD is defined as abnormal kidney structure or function present for greater than _______ months.

3

200

__________ is the most common form of the nephrotic syndrome in black patients.

FSGS


The prevalence in the US is more than 20,000 patients, with a yearly incidence of approximately 5,000 newly diagnosed cases per year.

200


Uric acid


Rhomboid; needle; rosette; barrels; hexagonal plates

Associated with hyperuricemia; gout; diabetes mellitus; obesity; tumor lysis syndrome; urine pH <6.0

200

This noncystic kidney disorder is associated with conical deformation of the lens, as well as sensorineural hearing loss.

Hereditary nephritis (aka Alport syndrome)


This is a collagen type IV-related nephropathy

200

True or False


The live attenuated Influenza vaccine should be administered annually to patients with ESRD

False


Patients with ESRD should only receive the inactivated influenza vaccine due to risks associated with the live vaccines in immunocompromised patients.

300

GFR 30-44 ml/min/1.73m2

G3b

300

__________ is the most common cause of the nephrotic syndrome in children.

Minimal change glomerulonephropathy (aka minimal change disease).

300


Calcium phosphate


Prism; needle; star-like clumps

Associated with distal renal tubular acidosis; urine pH >6.5; tumor lysis syndrome; acute phosphate nephropathy.

300

This X-lined recessive disorder is caused by an inborn error of glycophospholipid metabolism caused by deficiency of alpha-galactosidase A.

Fabry Disease


Progressive kidney disease, premature CAD, severe neuropathic pain, telangiectasias, angiokeratomas.

300

IV potassium can safely be infused peripherally at a rate of...

20mEq/h


Infusion through a central vein can be increased to 40mEq/h with close monitoring.

400

GFR 15-29 ml/min/1.73m2

G4

400

The diagnosis of glomerulonephritis is traditionally made by...

Kidney biopsy.


Serologic testing can aid in the diagnosis.

400


Cystine


Hexagonal morphology

Associated with cystinuria.

400

This autosomal dominant kidney disorder is characterized by tumors in many organs, primarily in the brain, eyes, heart, kidney, skin, and lungs. Renal angiomyolipomas occur in 75% of patients with this.

Tuberous Sclerosis Complex

400

Initial ECG manifestations with hyperkalemia include...

peaked precordial T waves and a shortened QT interval.

(With further progression, will see lengthening of the PR interval, loss of the P wave, widening of the QRS complex, a sine wave pattern, and then possible asystole)

500

G3a has a GFR range of...

45-59ml/min/1.73

500

Kidney biopsy in ___________ disease shows a crescentic glomerulonephritis on light microscopy and pathognomonic linear staining for IgG along the glomerular capillaries.

anti-GBM


Serologic testing for anti-GBM Abies is performed at time of diagnosis

500


Struvite (magnesium ammonium phosphate)


Coffin-lid morphology

Associated with alkaline urine due to chronic UTI with urease-producing organisms

500

This primarily autosomal dominant disorder is associated with type IV collagen variants causing GBM thinning, which results in hematuria without significant proteinuria or ensuing glomerulosclerosis.

Thin glomerular basement membrane disease (benign familial hematuria).

500

Gadolinium contrast used in MRI is associated with risk for ____________ and must be avoided in patients with an eGFR < ____________.

Nephrogenic Systemic Fibrosis (NSF); 30 ml/min/1.73m2