Blood Bank History
This man described the ABO blood group system in 1900 and received the Nobel prize in 1930.
Who is Landsteiner
This is the number of antigen in the ABO blood group system
what is 2 (A and B).
O is lack of A and B
AB is presence of both A and B
This is the antigen that used to be referred to as the "Rh factor"
RhD
This is the process of amplifying DNA by repeatedly denaturing, annealing primers and extending with DNA polymerase and dNTPs
This is the web-based interface the Red Cross provides to customers for placing orders for products and services
What is Bloodhub (or Connect)
This blood group system name is the species of monkeys whose red cells were injected into rabbits and the resulting antibodies studied
What is Rh (Rhesus)
This is the universal donor
What is O negative
These are the four common antigens encoded by the RHCE gene
This is a method used to decrease the chances of DNA carry-over in PCR-based testing.
What is UV light or decontaminating with bleach
This is the name of the serologic testing laboratories that perform patient antibody identifications and label red cell units as antigen negative
What are Immunohematology Reference Laboratories (IRLs)
These two men postulated that there were three closely linked genes encoding D, d, C, c, E and e
Who are Fisher and Race?
This is the universal recipient
What is AB positive
This is the number of genes in the RH blood group system
What is 2 (RHD and RHCE)
This is the genotyping method that involves digestion with bacteria-derived enzymes that cleave double-stranded DNA in a sequence specific manner
What is PCR-RFLP?
This is the organization that curates and publishes allele tables for all blood group systems
What is the ISBT (International Society for Blood Transfusion)?
This substance is first made available in 1967 for use in preventing hemolytic disease of the fetus and newborn from RhD incompatibility..
What is Rh immunoprophylaxis (or RhIg, or trade name RhoGam or WinRho)
This is the reaction of anti-A and anti-B with red cells of a donor or patient
What is the forward type?
This is a high prevalence antigen lacking in ~1% of individuals of African descent for which NML searches for antigen negative donors used for RH allele matching
What is hrB?
This is the software program NML uses to align a patient or donor blood group antigen gene sequence to the reference sequence
What is Sequencher?
What is U.
This blood group system, #034, includes a single antigen ,for which the gene was discovered in 2013, and the antigen negative phenotype was determined to be caused by a 17 base pair deletion by using whole exome sequencing of several antigen negative individuals.
What is VEL?
This is the organ transplantation where a group A2 individual can be the donor for a group B individual.
what is kidney?
This is the SNP for which the minor allele typically confers expression of both V and VS antigens
What is RHCE c.733C>G
This is the method used by NML to separately sequence two alleles carried by a donor or patient.
What is plasmid cloning.
This is the transcription factor that regulates expression of the FY blood group system in red blood cells (but not in other tissue types)
What is GATA-1?