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Don't antagonise me
I'm partial to MAT
That's ODious!
That's agonising!
(not that kind of) Potpourri
100

This medication can be given IN, IV, IM, SC for treatment of opioid overdose

What is naloxone?
100
This is the purpose of adding naloxone to preparations of buprenorphine.  
What is decrease ability for abuse of buprenorphine via IV injection?
100
Patients just release from jail may be at increased risk for overdose following relapse for this reason.  

What is loss of tolerance?

100
Opioid treatment programs dispensing methadone must be certified by this organisation and registered with this entity.  

What are SAMHSA and United States DEA?  

100

Tolerance develops to these effects of opioids but not usually to these.  

What are respiratory depression and euphoria but not miosis and constipation.  

200

To treat acute pain, the dose of opioid analgesic medication may need to be adjusted thusly to overcome naltrexone-based opioid receptor blockade

What is increased?

200

Due to its partial agonist characteristics, buprenorphine's opioid effects display a _____ effect, with increasingly higher doses not causing concomitant in symptoms such as respiratory depression, sedation, etc.

What is ceiling effect?

200
This is the half-life of naloxone and the reason why patients initially responsive to the medication may display sudden return of overdose symptoms, necessitating this course of action.  
What is 6.5 minutes and repeat administration of naloxone?
200

The highest risk for methadone-inducd respiratory depression is present within this period of time following first methadone dose.  

What is 24-72 hours?  

200
This is the only vital sign included on the COWS assessment instrument.  

What is resting pulse rate?

300

LFT's should be within this range of normal prior to starting naltrexone

What is 3x upper limit of normal range for AST and ALT?
300

Prescription of buprenorphine usually requires completion of X-waiver training, except in this situation.  

What is acute withdrawal in patients admitted to hospital for non-opioid use disorder conditions?

300

Accumulation of this opioid in the body in overdose (or even at therapeutic doses) can cause seizures.  

What is meperidine?

300

When used for chronic pain, methadone should be dosed according to this frequency.  

What is twice daily.  
300

These non-opioid medications can be used for symptomatic treatment of opioid withdrawal.  

What are clonidine, naproxen, loperamide, and zofran?

400

A patient should be free of all opioids (including long-acting opioids) for this many days prior to starting naltrexone

What is 10-14 days?

400

Patient should meet these COWS and opioid use criteria on date of induction with suboxone.  

What is COWS >8 or COWS<8 with no opioid use in 3 days and negative UDS?  
400
Most available "heroin" is contaminated with this opioid, which is of significantly higher potency and is frequently responsible for deaths related to accidental opioid overdose.  

What is fentanyl?

400
Due to a change in the elimination half-life of methadone in pregnant patients, the dose may need to be adjusted thusly.  

What is increased?

400

This MA-based resource offers patients "advice, information, and resources to help you take care of yourself and your family“.  

What is the Journey Recovery Project?
500

The long-acting form of naltrexone is given at those dose, via this route, with this frequency

What is 380 mg IM q28days?

500

Drugs such as carbamazepine and phenytoin may have this effect on buprenorphine metabolism, possibility necessitating ____dose of buprenorphine.  

What is induction of metabolism via CYP3A4 and increase in dose of buprenorphine?  

500

These are five physical findings of opioid overdose

Respiratory depression, altered mental status (drowsiness/unconsciousness), miosis, autonomic instability, pulmonary oedema

500
Patients starting methadone and those needing increase in dose should have this test performed due to the risk of this side-effect of methadone therapy.  
What is EKG and QTc prolongation?  
500

This MA resource "is a home visiting program...[which] match[es] [patients] with a family recovery support specialist who is a person in recovery with specialized training...and will walk beside [patients] on both your recovery and early parenting journey.“

What is „FIRST (Families In Recovery SupporT) Steps Together?