The Land of MHC
What is a processed exogenous peptide?
An intrinsic parameter that can be measured by a flow cytometer
What is granularity?
An antigenic determinant site produced by the folding of primary chain is called this
What is an epitope?
This type of hypersensitivity includes the reaction to poison ivy
What is Type IV Hypersensitivity?
What is several bands on electrophoresis of CSF?
In immunofixation electrophoresis, antibody is applied here
What is the top surface of the gel?
MHC molecules containing beta-2-microglobulin are determined by this
What are MHC-A, MHC-B, and MHC-C?
"Gating" is known as this
What is an electronic window separating sub-populations of cells?
Antigens found in different species that trigger a similar antibody response are called this
What are heterophile antigens?
Hypersensitivities to poison ivy and nickel are caused by this
What are macrophages that respond to haptens and T cells?
Systemic Lupus Erythematosus is characterized by the presence of this
What is anti ds-DNA?
For a passive agglutination test, these molecules are artificially bound to particles
What are antigen molecules?
A processed antigen first encounters and binds to MHC class II molecules in this compartment
What is the endosomal compartment?
Light signal in flow cytometry that could be used to provide information about the expression of a protein on the outer surface of a cell membrane
What is a red light emitted by phycoerythrin?
The ability to respond to antigen depends on these three factors
What are age, nutrition, and genetic predisposition?
This is an example of a condition involving a Type III hypersensitivity
What is Rheumatoid Arthritis?
Hashimoto's thyroiditis can best be differentiated from Grave's disease on the basis of this
What is a decreased thyroid hormone level?
A particle-counting immunoassay method counts the number of these
What are free latex particles?
Endogenous peptides binding to MHC-A,B, and C molecules on the surface of hepatocytes are critical for the response by these cells
What are cytotoxic T cells?
A fluorescent signal in flow cytometry is generated by these
What are fluorochromes that absorb energy from a laser beam and then release the energy as longer wavelength slides?
Characteristics of heterophile antigens is that they are found here
What is on unrelated plants and animals but cross react with some antibodies?
What is an Rh- mother is exposed to an Rh+ baby?
Antibodies to cyclic citrullinated proteins (anti-CCP) are specific diagnostic indicators for this disease
What is Rheumatoid Arthritis?
In a reverse agglutination test, this molecule is attached to a particle
What is an antibody?
MHC class I antigens are recognized by these cells
What are CD8+ T-Cells?
Fluorescently labeled antibodies are used in flow cytometry to determine this
What are proteins associated within a cell?
A plasma cell differs from a B-cell this way
What is only plasma cells secrete circulating antibodies?
Complement is responsible for tissue damage in this type of reaction
What is a Type III hypersensitivity?
This is associated with DiGeorge syndrome
What is a small or missing thymus?
If an Ouchterlony immunodiffusion pattern shows an arc equidistant between antigens A and B, this indicates that the antigens are this
What are identical?
The acute-phase protein haptoglobin binds to this
What is hemoglobin?
Fluorescence in flow cytometry are usually used to determine these parameters
What are extrinsic cell parameters?
Toll-like receptors bind to this
What is a pathogen associated molecular pattern?
This newly synthesized mediator has a mode of action similar to that of histamine
What is Heparin?
Leukocyte Adhesion Deficiency is caused by a defect in this
What is a defect in CD18?
A speckled nuclear pattern in an antinuclear antibody test indicate this
What is an antibody to an extractible nuclear antigen (ENA)?